2P1L

Structure of the Bcl-XL:Beclin 1 complex

Summary for 2P1L

• Entry DOI: 10.2210/pdb2p1l/pdb
• Descriptor: Apoptosis regulator Bcl-X, Beclin 1 (3 entities in total)
• Functional Keywords: apoptosis; autophagy; beclin; bh3 domain; bcl, apoptosis
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817; Cytoplasm . Beclin-1-C 35 kDa: Mitochondrion . Beclin-1-C 37 kDa: Mitochondrion : Q14457
• Total number of polymer chains: 8
• Total formula weight: 83553.02

Authors

Jeffrey, P.D.,Shi, Y.,Oberstein, A.L. (deposition date: 2007-03-05, release date: 2007-03-13, Last modification date: 2024-02-21)

• Primary citation: Oberstein, A.,Jeffrey, P.D.,Shi, Y.; Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein; J.Biol.Chem., 282:13123-13132, 2007; PubMed: 17337444; DOI: 10.1074/jbc.M700492200

Experimental method

X-RAY DIFFRACTION (2.5 Å)