2P1L
Structure of the Bcl-XL:Beclin 1 complex
Summary for 2P1L
Entry DOI | 10.2210/pdb2p1l/pdb |
Descriptor | Apoptosis regulator Bcl-X, Beclin 1 (3 entities in total) |
Functional Keywords | apoptosis; autophagy; beclin; bh3 domain; bcl, apoptosis |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 Cytoplasm . Beclin-1-C 35 kDa: Mitochondrion . Beclin-1-C 37 kDa: Mitochondrion : Q14457 |
Total number of polymer chains | 8 |
Total formula weight | 83553.02 |
Authors | Jeffrey, P.D.,Shi, Y.,Oberstein, A.L. (deposition date: 2007-03-05, release date: 2007-03-13, Last modification date: 2024-02-21) |
Primary citation | Oberstein, A.,Jeffrey, P.D.,Shi, Y. Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein J.Biol.Chem., 282:13123-13132, 2007 Cited by PubMed: 17337444DOI: 10.1074/jbc.M700492200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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