4O7Q
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5ZCK
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![BU of 5zck by Molmil](/molmil-images/mine/5zck) | Structure of the RIP3 core region | 分子名称: | SODIUM ION, peptide from Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Li, J, Wu, H. | 登録日 | 2018-02-18 | 公開日 | 2018-04-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.271 Å) | 主引用文献 | The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex. Cell, 173, 2018
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6BFN
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![BU of 6bfn by Molmil](/molmil-images/mine/6bfn) | Crystal structure of human IRAK1 | 分子名称: | Interleukin-1 receptor-associated kinase 1, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide | 著者 | Wang, L, Qiao, Q, Wu, H. | 登録日 | 2017-10-26 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Crystal structure of human IRAK1. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6BZE
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![BU of 6bze by Molmil](/molmil-images/mine/6bze) | Cryo-EM structure of BCL10 CARD filament | 分子名称: | B-cell lymphoma/leukemia 10 | 著者 | David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H. | 登録日 | 2017-12-23 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7DWO
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7DWN
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![BU of 7dwn by Molmil](/molmil-images/mine/7dwn) | Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Predicted DNA-binding transcriptional regulator | 著者 | Wang, W.W, Wu, H, He, J.H, Yu, F. | 登録日 | 2021-01-17 | 公開日 | 2021-07-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism. Int.J.Biol.Macromol., 183, 2021
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6JYL
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![BU of 6jyl by Molmil](/molmil-images/mine/6jyl) | The crosslinked complex of ISWI-nucleosome in the ADP.BeF-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | 著者 | Yan, L.J, Wu, H, Li, X.M, Gao, N, Chen, Z.C. | 登録日 | 2019-04-26 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling. Nat.Struct.Mol.Biol., 26, 2019
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6KW5
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![BU of 6kw5 by Molmil](/molmil-images/mine/6kw5) | The ClassC RSC-Nucleosome Complex | 分子名称: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | 著者 | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | 登録日 | 2019-09-06 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (10.13 Å) | 主引用文献 | Structure of the RSC complex bound to the nucleosome To Be Published
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6MB2
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6MJ2
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![BU of 6mj2 by Molmil](/molmil-images/mine/6mj2) | Human TRPM2 ion channel in a calcium- and ADPR-bound state | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily M member 2 | 著者 | Wang, L, Fu, T.M, Xia, S, Wu, H. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-02 | 実験手法 | ELECTRON MICROSCOPY (6.36 Å) | 主引用文献 | Structures and gating mechanism of human TRPM2. Science, 362, 2018
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6MIX
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6MIZ
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6K1P
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![BU of 6k1p by Molmil](/molmil-images/mine/6k1p) | The complex of ISWI-nucleosome in the ADP.BeF-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | 著者 | Yan, L.J, Wu, H, Li, X.M, Gao, N, Chen, Z.C. | 登録日 | 2019-05-10 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling. Nat.Struct.Mol.Biol., 26, 2019
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6N1H
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![BU of 6n1h by Molmil](/molmil-images/mine/6n1h) | Cryo-EM structure of ASC-CARD filament | 分子名称: | Apoptosis-associated speck-like protein containing a CARD | 著者 | Li, Y, Fu, T, Wu, H. | 登録日 | 2018-11-08 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N1I
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![BU of 6n1i by Molmil](/molmil-images/mine/6n1i) | Cryo-EM structure of NLRC4-CARD filament | 分子名称: | NLR family CARD domain-containing protein 4 | 著者 | Li, Y, Fu, T, Wu, H. | 登録日 | 2018-11-08 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1DS9
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![BU of 1ds9 by Molmil](/molmil-images/mine/1ds9) | SOLUTION STRUCTURE OF CHLAMYDOMONAS OUTER ARM DYNEIN LIGHT CHAIN 1 | 分子名称: | OUTER ARM DYNEIN | 著者 | Wu, H.W, Maciejewski, M.W, Marintchev, A, Benashski, S.E, Mullen, G.P, King, S.M. | 登録日 | 2000-01-07 | 公開日 | 2000-07-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a dynein motor domain associated light chain. Nat.Struct.Biol., 7, 2000
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1M9L
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![BU of 1m9l by Molmil](/molmil-images/mine/1m9l) | Relaxation-based Refined Structure Of Chlamydomonas Outer Arm Dynein Light Chain 1 | 分子名称: | Outer Arm Dynein Light Chain 1 | 著者 | Wu, H.W, Maciejewski, M.W, Marintchev, A, Benashski, S.E, Mullen, G.P, King, S.M. | 登録日 | 2002-07-29 | 公開日 | 2003-03-04 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Relaxation-based structure refinement and backbone molecular dynamics of the
Dynein motor domain-associated light chain Biochemistry, 42, 2003
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4WD5
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2H11
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![BU of 2h11 by Molmil](/molmil-images/mine/2h11) | Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-ADENOSYL-L-HOMOCYSTEINE, THIOCYANATE ION, ... | 著者 | Horton, J.R, Cheng, X. | 登録日 | 2006-05-15 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural basis of allele variation of human thiopurine-S-methyltransferase. Proteins, 67, 2007
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4ZSE
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4C1Q
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![BU of 4c1q by Molmil](/molmil-images/mine/4c1q) | Crystal structure of the PRDM9 SET domain in complex with H3K4me2 and AdoHcy. | 分子名称: | GLYCEROL, HISTONE H3.1, HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9, ... | 著者 | Mathioudakis, N, Cusack, S, Kadlec, J. | 登録日 | 2013-08-13 | 公開日 | 2013-10-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of Prdm9. Cell Rep., 5, 2013
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2JOL
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![BU of 2jol by Molmil](/molmil-images/mine/2jol) | Average NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei | 分子名称: | Putative G-nucleotide exchange factor | 著者 | Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S. | 登録日 | 2007-03-14 | 公開日 | 2007-03-27 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42 Biochem.J., 411, 2008
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2JOK
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![BU of 2jok by Molmil](/molmil-images/mine/2jok) | NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei | 分子名称: | Putative G-nucleotide exchange factor | 著者 | Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S. | 登録日 | 2007-03-14 | 公開日 | 2007-09-18 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42 Biochem.J., 411, 2008
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7T4E
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7T4D
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![BU of 7t4d by Molmil](/molmil-images/mine/7t4d) | Pore structure of pore-forming toxin Epx4 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Epx4 | 著者 | Xiong, X.Z, Dong, M, Yang, P, Abraham, J. | 登録日 | 2021-12-09 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors. Cell, 185, 2022
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