6MB2

Cryo-EM structure of the PYD filament of AIM2

Summary for 6MB2

• Entry DOI: 10.2210/pdb6mb2/pdb
• EMDB information: 9064
• Descriptor: Interferon-inducible protein AIM2, Green fluorescent protein (2 entities in total)
• Functional Keywords: filament, higher order, innate immunity, inflammasome, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 30
• Total formula weight: 551462.73

Authors

Lu, A.,Li, Y.,Wu, H. (deposition date: 2018-08-29, release date: 2018-09-05)

• Primary citation: Lu, A.,Li, Y.,Yin, Q.,Ruan, J.,Yu, X.,Egelman, E.,Wu, H.; Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2.; Cell Discov, 1:-, 2015; PubMed: 26583071; DOI: 10.1038/celldisc.2015.13

Experimental method

ELECTRON MICROSCOPY (5 Å)