6MB2

Cryo-EM structure of the PYD filament of AIM2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Interferon-inducible protein AIM2	polymer	94	10839.6	15	UniProt (O14862) Pfam (PF02758)	Homo sapiens (Human)	Absent in melanoma 2
2	AA, BA, CA, DA, P... (a, b, c, d, e...)	Green fluorescent protein	polymer	228	25924.6	15	UniProt (P42212) Pfam (PF01353)	Aequorea victoria (Jellyfish)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O: 1 - 93 (UniProt: O14862)

PDB	External Database	Details
Ala 0	-	expression tag
Gly 27	Phe 27	conflict

a, b, c, d, e, f, g, h, i, j, k, l, m, n, o: 2 - 229 (UniProt: P42212)

PDB	External Database	Details
-	Ser 65	deletion
-	Tyr 66	deletion
Cro 66	Gly 67	chromophore
Arg 80	Gln 80	conflict

Contents of the asymmetric unit

Polymers	Number of chains	30
	Total formula weight	551462.7
All*	Total formula weight	551462.7

*Water molecules are not included.