6MB2

Cryo-EM structure of the PYD filament of AIM2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Interferon-inducible protein AIM2	polymer	94	10839.6	15	UniProt (O14862) Pfam (PF02758) In PDB	Homo sapiens (Human)	Absent in melanoma 2
2	a, b, c, d, e...	Green fluorescent protein	polymer	228	25924.6	15	UniProt (P42212) Pfam (PF01353) In PDB	Aequorea victoria (Jellyfish)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O: 1 - 93 (UniProt: O14862)

PDB	External Database	Details
Ala 0	-	expression tag
Gly 27	Phe 27	conflict

a, b, c, d, e, f, g, h, i, j, k, l, m, n, o: 2 - 229 (UniProt: P42212)

PDB	External Database	Details
-	Ser 65	deletion
-	Tyr 66	deletion
Cro 66	Gly 67	chromophore
Arg 80	Gln 80	conflict

Contents of the asymmetric unit

Polymers	Number of chains	30
	Total formula weight	551462.7
All*	Total formula weight	551462.7

*Water molecules are not included.