6MB2

Cryo-EM structure of the PYD filament of AIM2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002218	biological_process	activation of innate immune response
A	0035458	biological_process	cellular response to interferon-beta
B	0002218	biological_process	activation of innate immune response
B	0035458	biological_process	cellular response to interferon-beta
C	0002218	biological_process	activation of innate immune response
C	0035458	biological_process	cellular response to interferon-beta
D	0002218	biological_process	activation of innate immune response
D	0035458	biological_process	cellular response to interferon-beta
E	0002218	biological_process	activation of innate immune response
E	0035458	biological_process	cellular response to interferon-beta
F	0002218	biological_process	activation of innate immune response
F	0035458	biological_process	cellular response to interferon-beta
G	0002218	biological_process	activation of innate immune response
G	0035458	biological_process	cellular response to interferon-beta
H	0002218	biological_process	activation of innate immune response
H	0035458	biological_process	cellular response to interferon-beta
I	0002218	biological_process	activation of innate immune response
I	0035458	biological_process	cellular response to interferon-beta
J	0002218	biological_process	activation of innate immune response
J	0035458	biological_process	cellular response to interferon-beta
K	0002218	biological_process	activation of innate immune response
K	0035458	biological_process	cellular response to interferon-beta
L	0002218	biological_process	activation of innate immune response
L	0035458	biological_process	cellular response to interferon-beta
M	0002218	biological_process	activation of innate immune response
M	0035458	biological_process	cellular response to interferon-beta
N	0002218	biological_process	activation of innate immune response
N	0035458	biological_process	cellular response to interferon-beta
O	0002218	biological_process	activation of innate immune response
O	0035458	biological_process	cellular response to interferon-beta
a	0006091	biological_process	generation of precursor metabolites and energy
a	0008218	biological_process	bioluminescence
b	0006091	biological_process	generation of precursor metabolites and energy
b	0008218	biological_process	bioluminescence
c	0006091	biological_process	generation of precursor metabolites and energy
c	0008218	biological_process	bioluminescence
d	0006091	biological_process	generation of precursor metabolites and energy
d	0008218	biological_process	bioluminescence
e	0006091	biological_process	generation of precursor metabolites and energy
e	0008218	biological_process	bioluminescence
f	0006091	biological_process	generation of precursor metabolites and energy
f	0008218	biological_process	bioluminescence
g	0006091	biological_process	generation of precursor metabolites and energy
g	0008218	biological_process	bioluminescence
h	0006091	biological_process	generation of precursor metabolites and energy
h	0008218	biological_process	bioluminescence
i	0006091	biological_process	generation of precursor metabolites and energy
i	0008218	biological_process	bioluminescence
j	0006091	biological_process	generation of precursor metabolites and energy
j	0008218	biological_process	bioluminescence
k	0006091	biological_process	generation of precursor metabolites and energy
k	0008218	biological_process	bioluminescence
l	0006091	biological_process	generation of precursor metabolites and energy
l	0008218	biological_process	bioluminescence
m	0006091	biological_process	generation of precursor metabolites and energy
m	0008218	biological_process	bioluminescence
n	0006091	biological_process	generation of precursor metabolites and energy
n	0008218	biological_process	bioluminescence
o	0006091	biological_process	generation of precursor metabolites and energy
o	0008218	biological_process	bioluminescence

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1290
Details	Domain: {"description":"Pyrin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00061","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	15
Details	Modified residue: {"description":"(Z)-2,3-didehydrotyrosine","evidences":[{"source":"PubMed","id":"8448132","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	30
Details	Cross-link: {"description":"5-imidazolinone (Ser-Gly)","evidences":[{"source":"PubMed","id":"8448132","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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