6NDJ

Crystal structure of human NLRP6 PYD domain with MBP fusion

Summary for 6NDJ

• Entry DOI: 10.2210/pdb6ndj/pdb
• Descriptor: Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera (2 entities in total)
• Functional Keywords: death domain fold, inflammasome, signaling protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 2
• Total formula weight: 104738.57

Authors

Shen, C.,Fu, T.M.,Wu, H. (deposition date: 2018-12-13, release date: 2019-01-23, Last modification date: 2024-03-13)

• Primary citation: Shen, C.,Lu, A.,Xie, W.J.,Ruan, J.,Negro, R.,Egelman, E.H.,Fu, T.M.,Wu, H.; Molecular mechanism for NLRP6 inflammasome assembly and activation.; Proc. Natl. Acad. Sci. U.S.A., 116:2052-2057, 2019; PubMed: 30674671; DOI: 10.1073/pnas.1817221116

Experimental method

X-RAY DIFFRACTION (2.27 Å)