4C1Q
Crystal structure of the PRDM9 SET domain in complex with H3K4me2 and AdoHcy.
Summary for 4C1Q
Entry DOI | 10.2210/pdb4c1q/pdb |
Descriptor | HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9, HISTONE H3.1, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total) |
Functional Keywords | transferase-peptide complex, histone methyltransferase, set domain h3k4me3, transferase/peptide |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Total number of polymer chains | 3 |
Total formula weight | 41658.85 |
Authors | Mathioudakis, N.,Cusack, S.,Kadlec, J. (deposition date: 2013-08-13, release date: 2013-10-16, Last modification date: 2023-12-20) |
Primary citation | Wu, H.,Mathioudakis, N.,Diagouraga, B.,Dong, A.,Dombrovski, L.,Baudat, F.,Cusack, S.,De Massy, B.,Kadlec, J. Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of Prdm9. Cell Rep., 5:13-, 2013 Cited by PubMed: 24095733DOI: 10.1016/J.CELREP.2013.08.035 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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