4QG6
| crystal structure of PKM2-Y105E mutant | 分子名称: | PROLINE, Pyruvate kinase PKM | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | 登録日 | 2014-05-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
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4QG8
| crystal structure of PKM2-K305Q mutant | 分子名称: | GLYCEROL, MAGNESIUM ION, MALONATE ION, ... | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | 登録日 | 2014-05-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
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8HFW
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6KL9
| Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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4QGC
| crystal structure of PKM2-K422R mutant | 分子名称: | GLYCEROL, POTASSIUM ION, Pyruvate kinase PKM, ... | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | 登録日 | 2014-05-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.296 Å) | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
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5TIK
| Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA | 分子名称: | Cysteine-rich protective antigen | 著者 | Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F. | 登録日 | 2016-10-03 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA. Elife, 6, 2017
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6KLB
| Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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4NM6
| Crystal structure of TET2-DNA complex | 分子名称: | 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', FE (II) ION, Methylcytosine dioxygenase TET2, ... | 著者 | Hu, L, Li, Z, Cheng, J, Rao, Q, Gong, W, Liu, M, Wang, P, Xu, Y. | 登録日 | 2013-11-14 | 公開日 | 2013-12-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.026 Å) | 主引用文献 | Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation. Cell(Cambridge,Mass.), 155, 2013
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4QG9
| crystal structure of PKM2-R399E mutant | 分子名称: | ACETATE ION, MAGNESIUM ION, Pyruvate kinase PKM | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | 登録日 | 2014-05-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
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2NBA
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2N59
| Solution Structure of R. palustris CsgH | 分子名称: | Putative uncharacterized protein CsgH | 著者 | Hawthorne, W.J, Taylor, J.D, Escalera-Maurer, A, Lambert, S, Koch, M, Scull, N, Sefer, L, Xu, Y, Matthews, S.J. | 登録日 | 2015-07-13 | 公開日 | 2016-05-11 | 実験手法 | SOLUTION NMR | 主引用文献 | Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones. Sci Rep, 6, 2016
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2MC5
| A bacteriophage transcription regulator inhibits bacterial transcription initiation by -factor displacement | 分子名称: | 45L | 著者 | Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S. | 登録日 | 2013-08-14 | 公開日 | 2014-03-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement. Nucleic Acids Res., 42, 2014
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2MC6
| A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement | 分子名称: | DNA-directed RNA polymerase subunit beta', RNA polymerase inhibitor p7 | 著者 | Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S. | 登録日 | 2013-08-15 | 公開日 | 2014-04-02 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement. Nucleic Acids Res., 42, 2014
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5ZCS
| 4.9 Angstrom Cryo-EM structure of human mTOR complex 2 | 分子名称: | Rapamycin-insensitive companion of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex 2 subunit MAPKAP1, ... | 著者 | Chen, X, Liu, M, Tian, Y, Wang, H, Wang, J, Xu, Y. | 登録日 | 2018-02-20 | 公開日 | 2018-03-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Cryo-EM structure of human mTOR complex 2. Cell Res., 28, 2018
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5YZ0
| Cryo-EM Structure of human ATR-ATRIP complex | 分子名称: | ATR-interacting protein, Serine/threonine-protein kinase ATR | 著者 | Rao, Q, Liu, M, Tian, Y, Wu, Z, Wang, H, Wang, J, Xu, Y. | 登録日 | 2017-12-11 | 公開日 | 2018-01-31 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Cryo-EM structure of human ATR-ATRIP complex. Cell Res., 28, 2018
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5XSU
| novel orally efficacious inhibitors complexed with PARP1 | 分子名称: | 6-fluoranyl-2-(4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | 著者 | Liu, Q, Xu, Y. | 登録日 | 2017-06-15 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors Eur J Med Chem, 145, 2018
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8I22
| Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | 分子名称: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester To Be Published
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8I6M
| Acyl-ACP synthetase structure bound to AMP-C18:1 | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, MAGNESIUM ION, ... | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-28 | 公開日 | 2024-01-31 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to AMP-C18:1 To Be Published
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8I35
| Acyl-ACP synthetase structure bound to oleic acid | 分子名称: | Acyl-acyl carrier protein synthetase, OLEIC ACID | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-16 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to oleic acid To Be Published
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8I3I
| Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 | 分子名称: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-17 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 To Be Published
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8I51
| Acyl-ACP synthetase structure bound to AMP-MC7 | 分子名称: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, ... | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-21 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to AMP-MC7 To Be Published
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8HZX
| Acyl-ACP synthetase structure-2 | 分子名称: | Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-09 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Acyl-ACP synthetase structure-2 To Be Published
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8I8E
| Acyl-ACP synthetase structure bound to C18:1-ACP | 分子名称: | 4'-PHOSPHOPANTETHEINE, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-02-04 | 公開日 | 2024-02-07 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to C18:1-ACP To Be Published
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8I49
| Acyl-ACP synthetase structure bound to ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-18 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to ATP. To Be Published
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8I8D
| Acyl-ACP synthetase structure bound to MC7-ACP | 分子名称: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-02-03 | 公開日 | 2024-02-07 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to MC7-ACP To Be Published
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