4W7T
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![BU of 4w7t by Molmil](/molmil-images/mine/4w7t) | Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990 | 分子名称: | (7S)-2-amino-4-methyl-7-phenyl-7,8-dihydroquinazolin-5(6H)-one, Heat shock protein HSP 90-alpha | 著者 | Bellamacina, C.R, Shafer, C.M, Bussiere, D. | 登録日 | 2014-08-22 | 公開日 | 2014-11-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design, Structure-Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990. J.Med.Chem., 57, 2014
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8I98
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![BU of 8i98 by Molmil](/molmil-images/mine/8i98) | Crystal structure of TePixD Y8F | 分子名称: | FLAVIN MONONUCLEOTIDE, Tll0078 protein | 著者 | Hu, R, Lin, L, Lu, Q. | 登録日 | 2023-02-06 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Structure of the BLUF Protein TePixD Y8F Mutant Progress in Biochemistry and Biophysics, 2023
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8Y8D
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![BU of 8y8d by Molmil](/molmil-images/mine/8y8d) | Structure of HCoV-HKU1C spike in the inactive-1up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8E
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![BU of 8y8e by Molmil](/molmil-images/mine/8y8e) | Structure of HCoV-HKU1C spike in the inactive-2up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8C
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![BU of 8y8c by Molmil](/molmil-images/mine/8y8c) | Structure of HCoV-HKU1C spike in the inactive-closed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y87
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![BU of 8y87 by Molmil](/molmil-images/mine/8y87) | Structure of HCoV-HKU1C spike in the functionally anchored-1up conformation with 1TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y89
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![BU of 8y89 by Molmil](/molmil-images/mine/8y89) | Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 2TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Wang, H.F, Zhang, X, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8G
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![BU of 8y8g by Molmil](/molmil-images/mine/8y8g) | Structure of HCoV-HKU1C spike in the glycan-activated-1up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y7Y
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![BU of 8y7y by Molmil](/molmil-images/mine/8y7y) | Local structure of HCoV-HKU1A spike in complex with TMPRSS2 and glycan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Wang, H.F, Zhang, X, Lu, Y, Liu, X, Sun, L, Yang, H.T. | 登録日 | 2024-02-05 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y88
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![BU of 8y88 by Molmil](/molmil-images/mine/8y88) | Structure of HCoV-HKU1C spike in the functionally anchored-2up conformation with 2TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8B
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![BU of 8y8b by Molmil](/molmil-images/mine/8y8b) | Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Wang, H.F, Zhang, X, Lu, Y.C, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8I
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![BU of 8y8i by Molmil](/molmil-images/mine/8y8i) | Structure of HCoV-HKU1C spike in the glycan-activated-3up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8A
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![BU of 8y8a by Molmil](/molmil-images/mine/8y8a) | Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 3TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8H
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![BU of 8y8h by Molmil](/molmil-images/mine/8y8h) | Structure of HCoV-HKU1C spike in the glycan-activated-2up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8F
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![BU of 8y8f by Molmil](/molmil-images/mine/8y8f) | Structure of HCoV-HKU1C spike in the glycan-activated-closed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8J
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![BU of 8y8j by Molmil](/molmil-images/mine/8y8j) | Local structure of HCoV-HKU1C spike in complex with glycan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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6W7F
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![BU of 6w7f by Molmil](/molmil-images/mine/6w7f) | Structure of EED bound to inhibitor 5285 | 分子名称: | 8-(6-cyclopropylpyridin-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-1-(methylsulfonyl)imidazo[1,5-c]pyrimidin-5-amine, GLYCEROL, Polycomb protein EED | 著者 | Petrunak, E.M, Stuckey, J.A. | 登録日 | 2020-03-19 | 公開日 | 2020-07-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development. J.Med.Chem., 63, 2020
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8Y7X
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![BU of 8y7x by Molmil](/molmil-images/mine/8y7x) | Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-05 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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6W7G
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![BU of 6w7g by Molmil](/molmil-images/mine/6w7g) | Structure of EED bound to inhibitor 1056 | 分子名称: | 8-(2,6-dimethylpyridin-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-1-(methylsulfonyl)imidazo[1,5-c]pyrimidin-5-amine, FORMIC ACID, Polycomb protein EED, ... | 著者 | Petrunak, E.M, Stuckey, J.A. | 登録日 | 2020-03-19 | 公開日 | 2020-07-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development. J.Med.Chem., 63, 2020
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4RPV
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![BU of 4rpv by Molmil](/molmil-images/mine/4rpv) | co-crystal structure of Pim1 with compound 3 | 分子名称: | (3S)-1-{6-[5-(2,6-difluorophenyl)-2H-indazol-3-yl]pyrazin-2-yl}piperidin-3-amine, Serine/threonine-protein kinase pim-1 | 著者 | Huang, X. | 登録日 | 2014-10-31 | 公開日 | 2015-02-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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8WBX
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![BU of 8wbx by Molmil](/molmil-images/mine/8wbx) | Cryo-EM structure of the ABCG25 bound to ABA | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABC transporter G family member 25 | 著者 | Xin, J, Yan, K.G. | 登録日 | 2023-09-10 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Structural insights into AtABCG25, an angiosperm-specific abscisic acid exporter. Plant Commun., 5, 2024
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8WAM
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![BU of 8wam by Molmil](/molmil-images/mine/8wam) | |
8WD6
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![BU of 8wd6 by Molmil](/molmil-images/mine/8wd6) | Cryo-EM structure of the ABCG25 | 分子名称: | ABC transporter G family member 25 | 著者 | Xin, J, Yan, K.G. | 登録日 | 2023-09-14 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Structural insights into AtABCG25, an angiosperm-specific abscisic acid exporter. Plant Commun., 5, 2024
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8WBA
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![BU of 8wba by Molmil](/molmil-images/mine/8wba) | Cryo-EM structure of the ABCG25 bound to CHS | 分子名称: | ABC transporter G family member 25, CHOLESTEROL HEMISUCCINATE | 著者 | Xin, J, Yan, K.G. | 登録日 | 2023-09-09 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into AtABCG25, an angiosperm-specific abscisic acid exporter. Plant Commun., 5, 2024
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3X3M
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![BU of 3x3m by Molmil](/molmil-images/mine/3x3m) | Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P212121 | 分子名称: | CALCIUM ION, ESX-1 secretion system protein EccB1 | 著者 | Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C. | 登録日 | 2015-01-24 | 公開日 | 2015-12-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase. Faseb J., 29, 2015
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