5WH1
 
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5ZFL
 | | Crystal structure of beta-lactamase PenP mutant E166Y | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase | | 著者 | Pan, X, Zhao, Y. | | 登録日 | 2018-03-06 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis.
Sci Rep, 10, 2020
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5ZG6
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5ZFT
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5YPO
 | | Crystal structure of PSD-95 GK domain in complex with phospho-SAPAP peptide | | 分子名称: | Disks large homolog 4, GLYCEROL, SAPAP | | 著者 | Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhang, R, Zhang, M. | | 登録日 | 2017-11-02 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
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5YPR
 | | Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor | | 分子名称: | Disks large homolog 4, Synthesized GK inhibitor | | 著者 | Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M. | | 登録日 | 2017-11-02 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.349 Å) | | 主引用文献 | Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
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7CR5
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6N05
 | | Structure of anti-crispr protein, AcrIIC2 | | 分子名称: | AcrIIC2 | | 著者 | Shah, M, Thavalingham, A, Maxwell, K.L, Moraes, T.F. | | 登録日 | 2018-11-06 | | 公開日 | 2019-06-05 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
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7TJE
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7TJG
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7TJM
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7TJD
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6XAF
 | | 1.9A crystal structure of the GTPase domain of Parkinson's disease-associated protein LRRK2 carrying R1398H | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION | | 著者 | Hoang, Q.Q, Liao, J, Huang, X, Park, Y, Wu, C.X. | | 登録日 | 2020-06-04 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.968 Å) | | 主引用文献 | Structural basis for conformational plasticity in the GTPase domain of the Parkinson's disease-associated protein LRRK2
To be Published
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8U89
 | | The structure of the PP2A-B56Delta holoenzyme mutant - E197K | | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | 著者 | Wu, C.G, Xing, Y. | | 登録日 | 2023-09-16 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8U1X
 | | The structure of the PP2A-B56Delta holoenzyme mutant - E197K | | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | 著者 | Wu, C.G, Xing, Y. | | 登録日 | 2023-09-04 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8HVS
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7KN3
 | | Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, S-B8 Fab heavy chain, ... | | 著者 | Liu, H, Zhu, X, Wilson, I.A. | | 登録日 | 2020-11-04 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
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7KN4
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8IAB
 | | The Arabidopsis CLCa transporter bound with chloride, ATP and PIP2 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Chloride channel protein CLC-a, ... | | 著者 | Yang, Z, Zhang, X, Zhang, P. | | 登録日 | 2023-02-08 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids.
Nat Commun, 14, 2023
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8IAD
 | | The Arabidopsis CLCa transporter bound with nitrate, ATP and PIP2 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Chloride channel protein CLC-a, MAGNESIUM ION, ... | | 著者 | Yang, Z, Zhang, X, Zhang, P. | | 登録日 | 2023-02-08 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids.
Nat Commun, 14, 2023
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8I6Y
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6JXT
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6JX0
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2AF5
 | | 2.5A X-ray Structure of Engineered OspA protein | | 分子名称: | Engineered Outer Surface Protein A (OspA) with the inserted two beta-hairpins | | 著者 | Makabe, K, Mcelheny, D, Tereshko, V, Hilyard, A, Koide, A, Koide, S. | | 登録日 | 2005-07-25 | | 公開日 | 2006-08-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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8G8C
 | | Crystal structure of DH1322.1 Fab in complex with HIV proximal MPER peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1322.1 heavy chain, DH1322.1 light chain, ... | | 著者 | Niyongabo, A, Janus, B.M, Ofek, G. | | 登録日 | 2023-02-17 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
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