2Z23
 
 | | Crystal structure of Y.pestis oligo peptide binding protein OppA with tri-lysine ligand | | 分子名称: | Periplasmic oligopeptide-binding protein, peptide (LYS)(LYS)(LYS) | | 著者 | Tanabe, M, Bertland, T, Mirza, O, Byrne, B, Brown, K.A. | | 登録日 | 2007-05-17 | | 公開日 | 2007-10-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains.
Acta Crystallogr.,Sect.D, 63, 2007
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2Z22
 | | Crystal structure of phosphate preplasmic binding protein psts from yersinia pestis | | 分子名称: | PHOSPHATE ION, Periplasmic phosphate-binding protein | | 著者 | Tanabe, M, Byrne, B, Brown, K.A, Mirza, O, Bertland, T. | | 登録日 | 2007-05-17 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains.
Acta Crystallogr.,Sect.D, 63, 2007
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5WR3
 | | Thermolysin, SFX liganded form with water-based carrier | | 分子名称: | CALCIUM ION, N-[(benzyloxy)carbonyl]-L-aspartic acid, Thermolysin, ... | | 著者 | Kunishima, N, Naitow, H, Matsuura, Y. | | 登録日 | 2016-11-29 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Protein-ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation
Acta Crystallogr D Struct Biol, 73, 2017
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7WU9
 | | Cryo-EM structure of the human EP3-Gi signaling complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Suno, R, Sugita, Y, Morimoto, K, Iwasaki, K, Kato, T, Kobayashi, T. | | 登録日 | 2022-02-07 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.375 Å) | | 主引用文献 | Structural insights into the G protein selectivity revealed by the human EP3-G i signaling complex.
Cell Rep, 40, 2022
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7YNH
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7WSI
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7DB6
 | | human melatonin receptor MT1 - Gi1 complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Okamoto, H.H, Kusakizako, T, Shihioya, W, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2020-10-19 | | 公開日 | 2021-08-18 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of the human MT 1 -G i signaling complex.
Nat.Struct.Mol.Biol., 28, 2021
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7VAF
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7VAG
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7VAD
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7VAE
 | | Cryo-EM structure of bovine NTCP complexed with YN69202Fab | | 分子名称: | Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Solute carrier family 10 (Sodium/bile acid cotransporter family), ... | | 著者 | Asami, J, Shimizu, T, Ohto, U. | | 登録日 | 2021-08-29 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Structure of the bile acid transporter and HBV receptor NTCP.
Nature, 606, 2022
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7VGR
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7VGS
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7D0I
 | | Cryo-EM structure of Schizosaccharomyces pombe Atg9 | | 分子名称: | Autophagy-related protein 9, Lauryl Maltose Neopentyl Glycol | | 著者 | Matoba, K, Tsutsumi, A, Kikkawa, M, Noda, N.N. | | 登録日 | 2020-09-10 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion.
Nat.Struct.Mol.Biol., 27, 2020
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7F8K
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3TRS
 | | The crystal structure of aspergilloglutamic peptidase from Aspergillus niger | | 分子名称: | Aspergillopepsin-2 heavy chain, Aspergillopepsin-2 light chain, DIMETHYL SULFOXIDE | | 著者 | Sasaki, H, Kubota, K, Lee, W.C, Ohtsuka, J, Kojima, M, Takahashi, K, Tanokura, M. | | 登録日 | 2011-09-10 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of an intermediate dimer of aspergilloglutamic peptidase that mimics the enzyme-activation product complex produced upon autoproteolysis.
J.Biochem., 152, 2012
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3WFE
 | | Reduced and cyanide-bound cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with antibody fragment | | 分子名称: | CALCIUM ION, CYANIDE ION, FE (III) ION, ... | | 著者 | Sato, N, Ishii, S, Hino, T, Sugimoto, H, Fukumori, Y, Shiro, Y, Tosha, T. | | 登録日 | 2013-07-18 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes.
Proteins, 82, 2014
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3WFC
 | | Reduced and carbonmonoxide-bound cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with antibody fragment | | 分子名称: | CALCIUM ION, CARBON MONOXIDE, FE (III) ION, ... | | 著者 | Sato, N, Ishii, S, Hino, T, Sugimoto, H, Fukumori, Y, Shiro, Y, Tosha, T. | | 登録日 | 2013-07-18 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes.
Proteins, 82, 2014
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3WFD
 | | Reduced and acetaldoxime-bound cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with antibody fragment | | 分子名称: | (1E)-N-hydroxyethanimine, CALCIUM ION, FE (III) ION, ... | | 著者 | Sato, N, Ishii, S, Hino, T, Sugimoto, H, Fukumori, Y, Shiro, Y, Tosha, T. | | 登録日 | 2013-07-18 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes.
Proteins, 82, 2014
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6OHD
 | | P38 in complex with T-3220137 | | 分子名称: | 3-(3-tert-butyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-4-methyl-N-(1,2-oxazol-3-yl)benzamide, Mitogen-activated protein kinase 14 | | 著者 | Lane, W, Saikatendu, K. | | 登録日 | 2019-04-05 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]Pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 2.
Chemmedchem, 14, 2019
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6M9L
 | | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping - compound 10 | | 分子名称: | 3-benzyl-6-[(2,4-difluorophenyl)amino]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, Mitogen-activated protein kinase 14 | | 著者 | Lane, W, Okada, K. | | 登録日 | 2018-08-23 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1.
Chemmedchem, 14, 2019
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6M95
 | | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping: compound 1 | | 分子名称: | (4-benzylpiperidin-1-yl)[2-methoxy-4-(methylsulfanyl)phenyl]methanone, Mitogen-activated protein kinase 14 | | 著者 | Lane, W, Okada, K. | | 登録日 | 2018-08-22 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1.
Chemmedchem, 14, 2019
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5WJJ
 | | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors | | 分子名称: | Mitogen-activated protein kinase 14, N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide | | 著者 | Snell, G.P, Okada, K, Bragstad, K, Sang, B.-C. | | 登録日 | 2017-07-23 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.
Bioorg. Med. Chem., 26, 2018
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6ANL
 | | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors | | 分子名称: | Mitogen-activated protein kinase 14, TAK-715 | | 著者 | Snell, G.P, Okada, K, Bragstad, K, Sang, B.-C. | | 登録日 | 2017-08-14 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.
Bioorg. Med. Chem., 26, 2018
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