7WU9
Cryo-EM structure of the human EP3-Gi signaling complex
Summary for 7WU9
Entry DOI | 10.2210/pdb7wu9/pdb |
EMDB information | 32824 |
Descriptor | Prostaglandin E2 receptor EP3 subtype, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (5 entities in total) |
Functional Keywords | gpcr, signal transduction, membrane protein, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 149511.54 |
Authors | Suno, R.,Sugita, Y.,Morimoto, K.,Iwasaki, K.,Kato, T.,Kobayashi, T. (deposition date: 2022-02-07, release date: 2022-08-17, Last modification date: 2023-10-04) |
Primary citation | Suno, R.,Sugita, Y.,Morimoto, K.,Takazaki, H.,Tsujimoto, H.,Hirose, M.,Suno-Ikeda, C.,Nomura, N.,Hino, T.,Inoue, A.,Iwasaki, K.,Kato, T.,Iwata, S.,Kobayashi, T. Structural insights into the G protein selectivity revealed by the human EP3-G i signaling complex. Cell Rep, 40:111323-111323, 2022 Cited by PubMed: 36103815DOI: 10.1016/j.celrep.2022.111323 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.375 Å) |
Structure validation
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