5WR3

Thermolysin, SFX liganded form with water-based carrier

Summary for 5WR3

• Entry DOI: 10.2210/pdb5wr3/pdb
• Related: 5WR2 5WR4 5WR5 5WR6
• Descriptor: Thermolysin, N-[(benzyloxy)carbonyl]-L-aspartic acid, ZINC ION, ... (5 entities in total)
• Functional Keywords: x-ray free-electron laser, serial femtosecond crystallography, microcrystal, structure-based drug design, hydrolase
• Biological source: Geobacillus stearothermophilus
• Cellular location: Secreted : P43133
• Total number of polymer chains: 1
• Total formula weight: 34853.29

Authors

Kunishima, N.,Naitow, H.,Matsuura, Y. (deposition date: 2016-11-29, release date: 2017-08-16, Last modification date: 2023-11-08)

• Primary citation: Naitow, H.,Matsuura, Y.,Tono, K.,Joti, Y.,Kameshima, T.,Hatsui, T.,Yabashi, M.,Tanaka, R.,Tanaka, T.,Sugahara, M.,Kobayashi, J.,Nango, E.,Iwata, S.,Kunishima, N.; Protein-ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation; Acta Crystallogr D Struct Biol, 73:702-709, 2017; PubMed: 28777085; DOI: 10.1107/S2059798317008919

Experimental method

X-RAY DIFFRACTION (2.1 Å)