7VOC
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![BU of 7voc by Molmil](/molmil-images/mine/7voc) | The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S | 分子名称: | (2~{S},3~{S},4~{S},5~{R},6~{R})-6-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid, Cytosylglucuronate decarboxylase, GLYCEROL, ... | 著者 | Hou, X.L, Zhou, J.H. | 登録日 | 2021-10-13 | 公開日 | 2022-05-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.62005424 Å) | 主引用文献 | Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S. J.Am.Chem.Soc., 144, 2022
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7VOB
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8X1V
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8HZY
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8HZV
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6CXD
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![BU of 6cxd by Molmil](/molmil-images/mine/6cxd) | Crystal structure of peptidase B from Yersinia pestis CO92 at 2.75 A resolution | 分子名称: | Peptidase B, SULFATE ION | 著者 | Woinska, M, Lipowska, J, Shabalin, I.G, Cymborowski, M, Grimshaw, S, Winsor, J, Shuvalova, L, Satchell, K.J, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-04-02 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
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6UUM
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6UUL
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![BU of 6uul by Molmil](/molmil-images/mine/6uul) | Crystal structure of broad and potent HIV-1 neutralizing antibody 438-D5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, D5 Fab Heavy Chain, ... | 著者 | Kumar, S, Wilson, I.A. | 登録日 | 2019-10-30 | 公開日 | 2020-09-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Sci Adv, 6, 2020
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6UUH
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6V6W
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7W5K
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![BU of 7w5k by Molmil](/molmil-images/mine/7w5k) | The C296A mutant of L-sorbosone dehydrogenase (SNDH) from Gluconobacter Oxydans WSH-004 | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J. | 登録日 | 2021-11-30 | 公開日 | 2023-03-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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7W5N
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![BU of 7w5n by Molmil](/molmil-images/mine/7w5n) | The crystal structure of the reduced form of Gluconobacter oxydans WSH-004 SNDH | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Li, D, Hou, X.D, Rao, Y.J, Yin, D.J, Zhou, J.W, Chen, J. | 登録日 | 2021-11-30 | 公開日 | 2023-03-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.988 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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7W5L
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![BU of 7w5l by Molmil](/molmil-images/mine/7w5l) | The crystal structure of the oxidized form of Gluconobacter oxydans WSH-004 SNDH | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent | 著者 | Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J. | 登録日 | 2021-11-30 | 公開日 | 2023-01-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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7WZX
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![BU of 7wzx by Molmil](/molmil-images/mine/7wzx) | The structure of a Twitch Radical SAM Dehydrogenase SpeY | 分子名称: | (2~{S},4~{S},6~{R})-2-[(2~{S},3~{R},5~{S},6~{R})-3,5-bis(methylamino)-2,4,6-tris(oxidanyl)cyclohexyl]oxy-6-methyl-4-oxidanyl-oxan-3-one, 4Fe-4S cluster-binding domain-containing protein, GLYCEROL, ... | 著者 | Hou, X.L, Zhou, J.H. | 登録日 | 2022-02-19 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.980013 Å) | 主引用文献 | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7WZV
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![BU of 7wzv by Molmil](/molmil-images/mine/7wzv) | The structure of a Twitch Radical SAM Dehydrogenase SpeY | 分子名称: | (1~{S},2~{R},4~{S},5~{R})-2,4-bis(methylamino)-6-[(2~{S},3~{R},4~{S},6~{R})-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-cyclohexane-1,3,5-triol, 1,2-ETHANEDIOL, 4Fe-4S cluster-binding domain-containing protein, ... | 著者 | Zhou, J.H, Hou, X.L. | 登録日 | 2022-02-19 | 公開日 | 2022-12-28 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.899313 Å) | 主引用文献 | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7X0B
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![BU of 7x0b by Molmil](/molmil-images/mine/7x0b) | The structure of a Twitch Radical SAM Dehydrogenase SpeY | 分子名称: | 4Fe-4S cluster-binding domain-containing protein, CHLORIDE ION, GLYCEROL, ... | 著者 | Hou, X.L, Zhou, J.H. | 登録日 | 2022-02-21 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.02027535 Å) | 主引用文献 | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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6KZ5
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![BU of 6kz5 by Molmil](/molmil-images/mine/6kz5) | Crystal Structure Analysis of the Csn-B-bounded NUR77 Ligand binding Domain | 分子名称: | Nuclear receptor subfamily 4 group A member 1, ethyl 2-[2-octanoyl-3,5-bis(oxidanyl)phenyl]ethanoate | 著者 | Hong, W, Chen, H, Wu, Q, Lin, T. | 登録日 | 2019-09-23 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (4.45 Å) | 主引用文献 | Blocking PPAR gamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression. Proc.Natl.Acad.Sci.USA, 117, 2020
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6OV8
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![BU of 6ov8 by Molmil](/molmil-images/mine/6ov8) | 2.6 Angstrom Resolution Crystal Structure of Aminopeptidase B from Escherichia coli str. K-12 substr. MG1655 | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Peptidase B, ... | 著者 | Minasov, G, Shuvalova, L, Wawrzak, Z, Kiryukhina, O, Grimshaw, S, Kwon, K, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-05-07 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Comparison of metal-bound and unbound structures of aminopeptidase B proteins from Escherichia coli and Yersinia pestis. Protein Sci., 29, 2020
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6OAD
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![BU of 6oad by Molmil](/molmil-images/mine/6oad) | 2.05 Angstrom Resolution Crystal Structure of Aminopeptidase B from Escherichia coli str. K-12 substr. MG1655. | 分子名称: | 1,2-ETHANEDIOL, BICARBONATE ION, CALCIUM ION, ... | 著者 | Minasov, G, Shuvalova, L, Wawrzak, Z, Kiryukhina, O, Grimshaw, S, Kwon, K, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-03-15 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Comparison of metal-bound and unbound structures of aminopeptidase B proteins from Escherichia coli and Yersinia pestis. Protein Sci., 29, 2020
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4Y87
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![BU of 4y87 by Molmil](/molmil-images/mine/4y87) | Crystal structure of phosphodiesterase 9 in complex with (R)-C33 (6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) | 分子名称: | 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
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4Y8C
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![BU of 4y8c by Molmil](/molmil-images/mine/4y8c) | Crystal structure of phosphodiesterase 9 in complex with (S)-C33 | 分子名称: | 6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
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4Y86
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![BU of 4y86 by Molmil](/molmil-images/mine/4y86) | Crystal structure of PDE9 in complex with racemic inhibitor C33 | 分子名称: | 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, 6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
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7MQV
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![BU of 7mqv by Molmil](/molmil-images/mine/7mqv) | Crystal structure of truncated (ACT domain removed) prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD | 分子名称: | CHLORIDE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Shabalin, I.G, Gritsunov, A, Gabryelska, A, Czub, M.P, Grabowski, M, Cooper, D.R, Christendat, D, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-05-06 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The crystal structure of Bacillus anthracis prephenate dehydrogenase identified an ACT regulatory domain and a novel mode of metabolic regulation for proteins within the prephenate dehydrogenase family of enzyme to be published
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6LCG
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![BU of 6lcg by Molmil](/molmil-images/mine/6lcg) | Structure of D-carbamoylase mutant from Nitratireductor indicus | 分子名称: | DI(HYDROXYETHYL)ETHER, N-carbamoyl-D-amino-acid hydrolase | 著者 | Liu, Y.F, Ni, Y, Xu, G.C, Dai, W. | 登録日 | 2019-11-18 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel Acs Catalysis, 10, 2020
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6LEI
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