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4FGM
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Crystal structure of the aminopeptidase N family protein Q5QTY1 from Idiomarina loihiensis. Northeast Structural Genomics Consortium Target IlR60.
分子名称: Aminopeptidase N family protein, MALEIC ACID, ZINC ION
著者Vorobiev, S, Su, M, Tong, T, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2012-06-04
公開日2012-08-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Crystal structure of the aminopeptidase N family protein Q5QTY1 from Idiomarina loihiensis.
To be Published
6Z1H
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Ancestral glycosidase (family 1)
分子名称: ANCESTRAL RECONSTRUCTED GLYCOSIDASE, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M, Gamiz-Arco, G, Gutierrez-Rus, L, Ibarra-Molero, B, Hoshino, Y, Petrovic, D, Romero-Rivera, A, Seelig, B, Kamerlin, S.C.L, Gaucher, E.A.
登録日2020-05-13
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase.
Nat Commun, 12, 2021
4FBE
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Crystal structure of the C136A/C164A variant of mitochondrial isoform of glutaminyl cyclase from Drosophila melanogaster
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, CG5976, isoform B, ...
著者Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T.
登録日2012-05-23
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
6Z47
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Smooth muscle myosin shutdown state heads region
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin heavy chain 11, ...
著者Scarff, C.A, Carrington, G, Casas Mao, D, Chalovich, J.M, Knight, P.J, Ranson, N.A, Peckham, M.
登録日2020-05-22
公開日2020-12-09
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Structure of the shutdown state of myosin-2.
Nature, 588, 2020
4F9P
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Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the 103.2 Single Chain Antibody
分子名称: 103.2 anti-BTN3A1 antibody fragment, Butyrophilin subfamily 3 member A1
著者Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J.
登録日2012-05-19
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.519 Å)
主引用文献The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
6Z4C
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The structure of the N-terminal domain of RssB from E. coli
分子名称: Regulator of RpoS
著者Zeth, K, Dimce, M, Terrence, D.M, Schuenemann, V, Dougan, D.
登録日2020-05-25
公開日2020-07-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight into the RssB-Mediated Recognition and Delivery of sigma s to the AAA+ Protease, ClpXP.
Biomolecules, 10, 2020
4FAO
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Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 2, ...
著者Townson, S.A, Martinez-Hackert, E, Greppi, C, Lowden, P, Sako, D, Liu, J, Ucran, J.A, Liharska, K, Underwood, K.W, Seehra, J, Kumar, R, Grinberg, A.V.
登録日2012-05-22
公開日2012-06-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.357 Å)
主引用文献Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex.
J.Biol.Chem., 287, 2012
4FE6
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Crystal Structure of HIV-1 Protease in Complex with an enamino-oxindole inhibitor
分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[({(3Z)-3-[1-(methylamino)ethylidene]-2-oxo-2,3-dihydro-1H-indol-5-yl}sulfonyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, HIV protease
著者Silva, A.M, Eissenstat, M, Guerassina, T, Gulnik, S, Afonina, E, Yu, B, Erickson, J, Ludke, D, Yokoe, H.
登録日2012-05-29
公開日2012-07-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enamino-oxindole HIV protease inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4F8L
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X-ray structure of PsaA from Yersinia pestis, in complex with galactose and AEBSF
分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, BROMIDE ION, GLYCINE, ...
著者Bao, R, Esser, L, Xia, D.
登録日2012-05-17
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F9U
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Structure of glycosylated glutaminyl cyclase from Drosophila melanogaster
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CG32412, ...
著者Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T.
登録日2012-05-21
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
6Z6F
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HDAC-PC
分子名称: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
6Z6O
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HDAC-TC
分子名称: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
6Z6H
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HDAC-DC
分子名称: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (8.55 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
6Z6P
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HDAC-PC-Nuc
分子名称: DNA (145-MER), HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
4F8Q
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BU of 4f8q by Molmil
Crystal Structure of the Human BTN3A2 Ectodomain
分子名称: Butyrophilin subfamily 3 member A2
著者Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J.
登録日2012-05-17
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3789 Å)
主引用文献The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
4F9V
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BU of 4f9v by Molmil
Structure of C113A/C136A mutant variant of glycosylated glutaminyl cyclase from Drosophila melanogaster
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, CG32412, DI(HYDROXYETHYL)ETHER, ...
著者Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T.
登録日2012-05-21
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
7XYO
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Crystal Structure of a M61 aminopeptidase family member from Myxococcus fulvus
分子名称: Aminopeptidase M61, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ...
著者Chen, X, Wang, X, Huo, L, Wu, D.
登録日2022-06-02
公開日2023-06-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery and Characterization of a Myxobacterial Lanthipeptide with Unique Biosynthetic Features and Anti-inflammatory Activity.
J.Am.Chem.Soc., 145, 2023
4O0N
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2.4 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii.
分子名称: Nucleoside diphosphate kinase, SULFATE ION
著者Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Shanmugam, D, Roos, D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-12-13
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
4ODI
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2.6 Angstrom Crystal Structure of Putative Phosphoglycerate Mutase 1 from Toxoplasma gondii
分子名称: Phosphoglycerate mutase PGMII, SODIUM ION
著者Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Shanmugam, D, Roos, D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-01-10
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
4V2B
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BU of 4v2b by Molmil
rat Unc5D Ig domain 1
分子名称: PROTEIN UNC5D
著者Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
登録日2014-10-08
公開日2014-11-05
最終更新日2015-07-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2A
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human Unc5A ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NETRIN RECEPTOR UNC5A
著者Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
登録日2014-10-08
公開日2014-11-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
5D9D
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Luciferin-regenerating enzyme solved by SAD using synchrotron radiation at room temperature
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION, ...
著者Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T.
登録日2015-08-18
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography.
Sci Rep, 5, 2015
5D96
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Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
分子名称: Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Sulfhydryl oxidase 1
著者Fass, D, Grossman, I.
登録日2015-08-18
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
8R6W
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Structure of the SFTSV L protein in a transcription-priming state with bound capped RNA [TRANSCRIPTION-PRIMING]
分子名称: RNA (5'-R(*(M7G)*AP*AP*A)-3'), RNA (5'-R(*AP*CP*AP*C)-3'), RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*G)-3'), ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Busch, C, Milewski, M, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-11-23
公開日2024-04-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural snapshots of phenuivirus cap-snatching and transcription.
Nucleic Acids Res., 52, 2024
8R6Y
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Structure of the SFTSV L protein stalled in a transcription-specific early elongation state with bound capped RNA [TRANSCRIPTION-EARLY-ELONGATION]
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(*(M7G)*AP*AP*A)-3'), ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Busch, C, Milewski, M, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-11-23
公開日2024-04-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural snapshots of phenuivirus cap-snatching and transcription.
Nucleic Acids Res., 52, 2024

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