8R6W

Structure of the SFTSV L protein in a transcription-priming state with bound capped RNA [TRANSCRIPTION-PRIMING]

Summary for 8R6W

• Entry DOI: 10.2210/pdb8r6w/pdb
• Related: 8R6U 8R6W 8R6Y
• EMDB information: 18967
• Descriptor: RNA-directed RNA polymerase L, RNA (5'-R(*AP*CP*AP*C)-3'), RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*G)-3'), ... (5 entities in total)
• Functional Keywords: sftsv, rna-dependent rna polymerase, viral rna, viral protein
• Biological source: SFTS virus AH12; More
• Total number of polymer chains: 5
• Total formula weight: 261494.29

Authors

Williams, H.M.,Thorkelsson, S.R.,Vogel, D.,Busch, C.,Milewski, M.,Cusack, S.,Grunewald, K.,Quemin, E.R.J.,Rosenthal, M. (deposition date: 2023-11-23, release date: 2024-04-24, Last modification date: 2024-06-19)

• Primary citation: Williams, H.M.,Thorkelsson, S.R.,Vogel, D.,Busch, C.,Milewski, M.,Cusack, S.,Grunewald, K.,Quemin, E.R.J.,Rosenthal, M.; Structural snapshots of phenuivirus cap-snatching and transcription.; Nucleic Acids Res., 52:6049-6065, 2024; PubMed: 38709882; DOI: 10.1093/nar/gkae330

Experimental method

ELECTRON MICROSCOPY (3.35 Å)