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8R6W

Structure of the SFTSV L protein in a transcription-priming state with bound capped RNA [TRANSCRIPTION-PRIMING]

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA-directed RNA polymerase Lpolymer2084235698.51UniProt (U3GU88)
UniProt (by SIFTS) (I0DF35)
SFTS virus AH12
2B
(G)
RNA (5'-R(*AP*CP*AP*C)-3')polymer165094.21SFTS virus AH12
3C
(P)
RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*G)-3')polymer206452.01SFTS virus AH12
4D
(T)
RNA (5'-R(P*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3')polymer268386.01SFTS virus AH12
5E
(C)
RNA (5'-R(*(M7G)*AP*AP*A)-3')polymer185863.61SFTS virus AH12
Sequence modifications
A: 1 - 2084 (UniProt: U3GU88)
PDBExternal DatabaseDetails
Ala 112Asp 112engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight261494.3
All*Total formula weight261494.3
*Water molecules are not included.

251801

PDB entries from 2026-04-08

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