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6AX3
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BU of 6ax3 by Molmil
Complex structure of JMJD5 and Symmetric Dimethyl-Arginine (SDMA)
分子名称: 2-OXOGLUTARIC ACID, Lysine-specific demethylase 8, N3, ...
著者Lee, S, Liu, H, Wang, Y, Dai, S, Zhang, G.
登録日2017-09-06
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
4ZHQ
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BU of 4zhq by Molmil
Crystal structure of Tubulin-Stathmin-TTL-MMAE Complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Wang, Y, Zhang, R.
登録日2015-04-26
公開日2016-07-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZI7
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BU of 4zi7 by Molmil
CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-HTI286 COMPLEX
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Wang, Y, Zhang, R.
登録日2015-04-27
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
8IPT
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BU of 8ipt by Molmil
Cryo-EM structure of heme transporter CydDC from Escherichia coli in the occluded ATP bound state
分子名称: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPS
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BU of 8ips by Molmil
Cryo-EM structure of heme transporter CydDC from Escherichia coli in the inward facing heme loading state
分子名称: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPR
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BU of 8ipr by Molmil
Cryo-EM structure of heme transporter CydDC from Mycobacterium smegmatis in the outward facing ATP bound state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC, MAGNESIUM ION, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPQ
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BU of 8ipq by Molmil
Cryo-EM structure of heme transporter CydDC from Mycobacterium smegmatis in the inward facing apo state
分子名称: Component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC, Transmembrane ATP-binding protein ABC transporter cydD
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8WW2
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BU of 8ww2 by Molmil
GPR3/Gs complex
分子名称: CHOLESTEROL HEMISUCCINATE, G-protein coupled receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者He, Y, Xiong, Y.
登録日2023-10-24
公開日2024-02-14
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Identification of oleic acid as an endogenous ligand of GPR3.
Cell Res., 34, 2024
7E5Y
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BU of 7e5y by Molmil
Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD
分子名称: 2B11 Fab Heavy chain, 2B11 Fab Light chain, Spike protein S1
著者Wu, H, Yu, F, Wang, Q.S, Zhou, H, Wang, W.W, Zhao, T, Pan, Y.B, Yang, X.M.
登録日2021-02-21
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries.
Cell Discov, 7, 2021
6IZL
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BU of 6izl by Molmil
Cryo-EM structure of Mud crab tombus-like virus at 3.3 Angstroms resolution
分子名称: mud crab tombus-like virus
著者Zhang, Q, Gao, Y.
登録日2018-12-19
公開日2019-01-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-electron Microscopy Structures of Novel Viruses from Mud CrabScylla paramamosainwith Multiple Infections.
J. Virol., 93, 2019
4MC7
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BU of 4mc7 by Molmil
Crystal structure of a subtype N11 neuraminidase-like protein of A/flat-faced bat/Peru/033/2010 (H18N11)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE
著者Yang, H, Carney, P.J, Chang, J.C, Guo, Z, Stevens, J.
登録日2013-08-21
公開日2013-10-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献New world bats harbor diverse influenza a viruses.
Plos Pathog., 9, 2013
4XXB
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BU of 4xxb by Molmil
Crystal structure of human MDM2-RPL11
分子名称: 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ...
著者Zheng, J, Chen, Z.
登録日2015-01-30
公開日2015-08-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation
Genes Dev., 29, 2015
7WOI
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BU of 7woi by Molmil
Structure of the shaft pilin Spa2 from Corynebacterium glutamicum
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Spa2
著者Wu, Y.F, Wang, L.T, Huang, Y.Y, Zhong, C, Zhou, J.
登録日2022-01-21
公開日2023-01-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Accelerating the design of pili-enabled living materials using an integrative technological workflow.
Nat.Chem.Biol., 2023
8WMI
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BU of 8wmi by Molmil
Cryo-EM structure of DiCas7-11 mutant in complex with crRNA
分子名称: CRISPR-associated RAMP family protein, ZINC ION, crRNA (39-MER)
著者Ma, H.Y, Tang, X.D.
登録日2023-10-03
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
8WM4
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BU of 8wm4 by Molmil
Cryo-EM structure of DiCas7-11 in complex with crRNA
分子名称: CRISPR-associated RAMP family protein, ZINC ION, crRNA (38-MER)
著者Ma, H.Y, Tang, X.D.
登録日2023-10-02
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
8WML
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BU of 8wml by Molmil
Cryo-EM structure of Cas7-11-crRNA bound to N-terminal of TPR-CHAT
分子名称: CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ...
著者Ma, H.Y, Tang, X.D.
登録日2023-10-03
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
7WP6
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BU of 7wp6 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 36H6 heavy chain, ...
著者Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
登録日2022-01-23
公開日2023-03-01
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
7WP8
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BU of 7wp8 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ...
著者Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
登録日2022-01-23
公開日2023-03-08
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
8WMC
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BU of 8wmc by Molmil
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
分子名称: CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (38-MER), ...
著者Ma, H.Y, Tang, X.D.
登録日2023-10-03
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
5E54
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BU of 5e54 by Molmil
Two apo structures of the adenine riboswitch aptamer domain determined using an X-ray free electron laser
分子名称: MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2015-10-07
公開日2016-11-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
6EIS
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BU of 6eis by Molmil
DYRK1A in complex with JWC-055
分子名称: 1-[4-fluoranyl-2-(trifluoromethyl)phenyl]-9-(1~{H}-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
著者Rothweiler, U.
登録日2017-09-19
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors.
J. Med. Chem., 61, 2018
4HBK
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BU of 4hbk by Molmil
Structure of the Aldose Reductase from Schistosoma japonicum
分子名称: Aldo-keto reductase family 1, member B4 (Aldose reductase)
著者Liu, J, Cheng, J, Zhang, X, Yang, Z, Hu, W, Xu, Y.
登録日2012-09-28
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds.
Parasit Vectors, 6, 2013
6WIR
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BU of 6wir by Molmil
Fab antigen complex
分子名称: Fab heavy chain, Fab light chain, Interleukin-17A
著者Antonysamy, S.
登録日2020-04-10
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
6JLQ
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BU of 6jlq by Molmil
Crystal structure of human USP46-WDR48-WDR20 complex
分子名称: GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ...
著者Zhu, H, Zhang, T, Ding, J.
登録日2019-03-06
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Structural insights into the activation of USP46 by WDR48 and WDR20.
Cell Discov, 5, 2019
5XK7
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BU of 5xk7 by Molmil
Crystal structure of Isosesquilavandulyl Diphosphate Synthase from Streptomyces sp. strain CNH-189 in complex with DMAPP
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, ...
著者Ko, T.P, Guo, R.T, Liu, W, Chen, C.C, Gao, J.
登録日2017-05-05
公開日2018-01-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.911 Å)
主引用文献"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.
Angew. Chem. Int. Ed. Engl., 57, 2018

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