4HBK

Structure of the Aldose Reductase from Schistosoma japonicum

Summary for 4HBK

• Entry DOI: 10.2210/pdb4hbk/pdb
• Descriptor: Aldo-keto reductase family 1, member B4 (Aldose reductase) (2 entities in total)
• Functional Keywords: aldose reductase, oxidoreductase
• Biological source: Schistosoma japonicum (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 39235.89

Authors

Liu, J.,Cheng, J.,Zhang, X.,Yang, Z.,Hu, W.,Xu, Y. (deposition date: 2012-09-28, release date: 2013-06-26, Last modification date: 2023-09-20)

• Primary citation: Liu, J.,Dyer, D.,Cheng, J.,Wang, J.,Wang, S.,Yang, Z.,Wang, X.,Hu, W.; Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds.; Parasit Vectors, 6:162-162, 2013; PubMed: 23734964; DOI: 10.1186/1756-3305-6-162

Experimental method

X-RAY DIFFRACTION (2.2 Å)