8UD3
 
 | | SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form | | 分子名称: | Non-structural protein 15, RNA (35-MER) | | 著者 | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | | 登録日 | 2023-09-28 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 2024
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8UD5
 | | SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 2 | | 分子名称: | Non-structural protein 15, RNA (35-MER) | | 著者 | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | | 登録日 | 2023-09-28 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 2024
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8UD4
 | | SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 1 | | 分子名称: | Non-structural protein 15, RNA (35-MER) | | 著者 | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | | 登録日 | 2023-09-28 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 2024
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8UD2
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4H0N
 | | Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant | | 分子名称: | CALCIUM ION, DNMT2, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Li, S, Du, J, Yang, H, Yin, J, Zhong, J, Ding, J. | | 登録日 | 2012-09-09 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.712 Å) | | 主引用文献 | Functional and structural characterization of DNMT2 from Spodoptera frugiperda.
J Mol Cell Biol, 5, 2013
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4KTH
 | | Structure of A/Hubei/1/2010 H5 HA | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | 著者 | Shore, D.A, Yang, H, Carney, P.J, Chang, J.C, Stevens, J. | | 登録日 | 2013-05-20 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Antigenic Variation among Diverse Clade 2 H5N1 Viruses.
Plos One, 8, 2013
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4KW1
 | | Structure of a/egypt/n03072/2010 h5 ha | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Shore, D.A, Yang, H, Carney, P.J, Chang, J.C, Stevens, J. | | 登録日 | 2013-05-23 | | 公開日 | 2014-06-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and antigenic variation among diverse clade 2 H5N1 viruses.
Plos One, 8, 2013
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4LTU
 | | Crystal Structure of Ferredoxin from Rhodopseudomonas palustris HaA2 | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, Ferredoxin | | 著者 | Zhou, W.H, Zhang, T, Yang, H, Bell, S.G, Wong, L.-L. | | 登録日 | 2013-07-24 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure of Ferredoxin from Rhodopseudomonas palustris HaA2
To be Published
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2JXB
 | | Structure of CD3epsilon-Nck2 first SH3 domain complex | | 分子名称: | T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 | | 著者 | Takeuchi, K, Yang, H, Ng, E, Park, S, Sun, Z.J, Reinherz, E.L, Wagner, G. | | 登録日 | 2007-11-09 | | 公開日 | 2008-09-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
J.Mol.Biol., 380, 2008
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5XQ1
 | | Structural basis of kindlin-mediated integrin recognition and activation | | 分子名称: | Fermitin family homolog 2,Integrin beta-3 | | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | | 登録日 | 2017-06-05 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.954 Å) | | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XPY
 | | Structural basis of kindlin-mediated integrin recognition and activation | | 分子名称: | ACETATE ION, Fermitin family homolog 2, GLYCEROL | | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | | 登録日 | 2017-06-05 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XPZ
 | | Structural basis of kindlin-mediated integrin recognition and activation | | 分子名称: | Fermitin family homolog 2, GLYCEROL | | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | | 登録日 | 2017-06-05 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XQ0
 | | Structural basis of kindlin-mediated integrin recognition and activation | | 分子名称: | Fermitin family homolog 2,Integrin beta-1, GLYCEROL | | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | | 登録日 | 2017-06-05 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ZHZ
 | | Crystal structure of the apurinic/apyrimidinic endonuclease IV from Mycobacterium tuberculosis | | 分子名称: | Probable endonuclease 4, SULFATE ION, ZINC ION | | 著者 | Zhang, W, Xu, Y, Yan, M, Li, S, Wang, H, Yang, H, Zhou, W, Rao, Z. | | 登録日 | 2018-03-13 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Crystal structure of the apurinic/apyrimidinic endonuclease IV from Mycobacterium tuberculosis.
Biochem. Biophys. Res. Commun., 498, 2018
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2G9T
 | | Crystal structure of the SARS coronavirus nsp10 at 2.1A | | 分子名称: | ZINC ION, orf1a polyprotein | | 著者 | Su, D, Lou, Z, Yang, H, Sun, F, Rao, Z. | | 登録日 | 2006-03-07 | | 公開日 | 2006-08-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10
J.Virol., 80, 2006
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7VH8
 | | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332 | | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase, DIMETHYL SULFOXIDE | | 著者 | Zhao, Y, Zhang, Q, Yang, H, Rao, Z. | | 登録日 | 2021-09-21 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332.
Protein Cell, 13, 2022
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6M49
 | | cryo-EM structure of Scap/Insig complex in the present of 25-hydroxyl cholesterol. | | 分子名称: | 25-HYDROXYCHOLESTEROL, Insulin-induced gene 2 protein, Sterol regulatory element-binding protein cleavage-activating protein,Sterol regulatory element-binding protein cleavage-activating protein | | 著者 | Yan, R, Cao, P, Song, W, Qian, H, Du, X, Coates, H.W, Zhao, X, Li, Y, Gao, S, Gong, X, Liu, X, Sui, J, Lei, J, Yang, H, Brown, A.J, Zhou, Q, Yan, C, Yan, N. | | 登録日 | 2020-03-06 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.
Science, 371, 2021
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7VUX
 | | Complex structure of PD1 and 609A-Fab | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X. | | 登録日 | 2021-11-04 | | 公開日 | 2021-11-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties.
Mabs, 14, 2022
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6B3M
 | | The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 70-1F02 Fab Heavy Chain, ... | | 著者 | Shore, D.A, Yang, H, Stevens, J. | | 登録日 | 2017-09-22 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.92 Å) | | 主引用文献 | Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge.
J. Virol., 92, 2018
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6B44
 | | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA | | 分子名称: | CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ... | | 著者 | Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S. | | 登録日 | 2017-09-25 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6B45
 | | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex | | 分子名称: | CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ... | | 著者 | Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S. | | 登録日 | 2017-09-25 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6B47
 | | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF2 | | 分子名称: | Anti-CRISPR protein AcrF2, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | 著者 | Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S. | | 登録日 | 2017-09-25 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6B48
 | | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF10 | | 分子名称: | Anti-CRISPR protein AcrF10, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | 著者 | Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S. | | 登録日 | 2017-09-25 | | 公開日 | 2017-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6BWM
 | | Crystal structure of the TRPV2 ion channel | | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily V member 2 | | 著者 | Zubcevic, L, Le, S, Yang, H, Lee, S.Y. | | 登録日 | 2017-12-15 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Conformational plasticity in the selectivity filter of the TRPV2 ion channel.
Nat. Struct. Mol. Biol., 25, 2018
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6B46
 | | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1 | | 分子名称: | Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy3, ... | | 著者 | Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S. | | 登録日 | 2017-09-25 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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