6B3M

The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin

Summary for 6B3M

Entry DOI	10.2210/pdb6b3m/pdb
Descriptor	Hemagglutinin HA1, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
Functional Keywords	antibody, hemagglutinin, influenza, viral protein-immune system complex, viral protein/immune system
Biological source	unidentified influenza virus More
Total number of polymer chains	24
Total formula weight	645832.19
Authors	Shore, D.A.,Yang, H.,Stevens, J. (deposition date: 2017-09-22, release date: 2018-06-13, Last modification date: 2023-10-04)
Primary citation	Nachbagauer, R.,Shore, D.,Yang, H.,Johnson, S.K.,Gabbard, J.D.,Tompkins, S.M.,Wrammert, J.,Wilson, P.C.,Stevens, J.,Ahmed, R.,Krammer, F.,Ellebedy, A.H. Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. J. Virol., 92:-, 2018 Cited by PubMed: 29899095 DOI: 10.1128/JVI.00949-18 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.92 Å)

Structure validation