6B3M
The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, G, K, Q... | Hemagglutinin HA1 | polymer | 330 | 37607.7 | 6 | UniProt (Q5EP31) Pfam (PF00509) UniProt (by SIFTS) (Q6DQ33) In PDB | unidentified influenza virus | |
| 2 | B, F, H, L, R... | Hemagglutinin HA2 | polymer | 181 | 20881.1 | 6 | UniProt (A0A182DWE1) Pfam (PF00509) In PDB | unidentified influenza virus | |
| 3 | C, I, M, O, V... | 70-1F02 Fab Heavy Chain | polymer | 221 | 23534.4 | 6 | Homo sapiens (Human) | ||
| 4 | P, U, J, D, W... | 70-1F02 Fab Light Chain | polymer | 215 | 23440.0 | 6 | Homo sapiens (Human) | ||
| 5 | k, o, p, X | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 4 | In PDB GlyTouCan (G48068RF) | |||
| 6 | Z | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 7 | a, b, c, d, e... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 8 | g | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G21381MC) | |||
| 9 | i, l | alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G08748CW) | |||
| 10 | j | beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G57221JN) | |||
| 11 | A, E, F, G, K... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 12 | C | beta-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (BMA) |
Sequence modifications
B, F, H, L, R, T: 1 - 181 (UniProt: A0A182DWE1)
| PDB | External Database | Details |
|---|---|---|
| Glu 147 | Lys 147 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 632779.1 | |
| Branched | Number of molecules | 18 |
| Total formula weight | 10882.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2171.0 | |
| All* | Total formula weight | 645832.2 |
