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6KB7
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BU of 6kb7 by Molmil
X-ray structure of human PPARalpha ligand binding domain-Wy14643 co-crystals obtained by delipidation and cross-seeding
分子名称: 2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC ACID, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KAY
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BU of 6kay by Molmil
X-ray structure of human PPARalpha ligand binding domain-GW7647 co-crystals obtained by soaking
分子名称: 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Suda, K, Saito, K, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.735 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KB3
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BU of 6kb3 by Molmil
X-ray structure of human PPARalpha ligand binding domain-GW7647 co-crystals obtained by delipidation and cross-seeding
分子名称: 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KB2
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BU of 6kb2 by Molmil
X-ray structure of human PPARalpha ligand binding domain-Wy14643 co-crystals obtained by soaking
分子名称: 2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC ACID, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Suda, K, Saito, K, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KB9
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BU of 6kb9 by Molmil
X-ray structure of human PPARalpha ligand binding domain-pemafibrate co-crystals obtained by cross-seeding
分子名称: (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
7CEG
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BU of 7ceg by Molmil
Crystal structure of the complex between mouse PTP delta and neuroligin-3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3
著者Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
登録日2020-06-23
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
7CEE
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BU of 7cee by Molmil
Crystal structure of mouse neuroligin-3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-3
著者Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
登録日2020-06-23
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.763 Å)
主引用文献Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
6KAZ
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BU of 6kaz by Molmil
X-ray structure of human PPARalpha ligand binding domain-pemafibrate co-crystals obtained by soaking
分子名称: (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Suda, K, Saito, K, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KB5
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BU of 6kb5 by Molmil
X-ray structure of human PPARalpha ligand binding domain-5,8,11,14-eicosatetraynoic Acid (ETYA) co-crystals obtained by delipidation and cross-seeding
分子名称: GLYCEROL, Peroxisome proliferator-activated receptor alpha, icosa-5,8,11,14-tetraynoic acid
著者Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KBA
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BU of 6kba by Molmil
X-ray structure of human PPARalpha ligand binding domain-Wy14643 co-crystals obtained by co-crystallization
分子名称: 2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC ACID, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Suda, K, Saito, K, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KAX
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BU of 6kax by Molmil
X-ray structure of human PPARalpha ligand binding domain-intrinsic fatty acid (E. coli origin) co-crystals obtained by cross-seeding
分子名称: GLYCEROL, PALMITIC ACID, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Suda, K, Saito, K, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KB4
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BU of 6kb4 by Molmil
X-ray structure of human PPARalpha ligand binding domain-pemafibrate co-crystals obtained by delipidation and cross-seeding
分子名称: (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6KB6
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BU of 6kb6 by Molmil
X-ray structure of human PPARalpha ligand binding domain-tetradecylthioacetic acid (TTA) co-crystals obtained by delipidation and cross-seeding
分子名称: 2-tetradecylsulfanylethanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.431 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6T9C
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BU of 6t9c by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand NV1346 (3a)
分子名称: 4-hexoxy-~{N}-[(2~{S})-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]benzamide, Peroxisome proliferator-activated receptor gamma
著者Pochetti, G, Montanari, R, Capelli, D.
登録日2019-10-27
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into PPAR gamma Phosphorylation and Its Inhibition Mechanism.
J.Med.Chem., 63, 2020
3AUJ
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BU of 3auj by Molmil
Structure of diol dehydratase complexed with glycerol
分子名称: CALCIUM ION, COBALAMIN, Diol dehydrase alpha subunit, ...
著者Yamanishi, M, Kinoshita, K, Fukuoka, M, Shibata, T, Tobimatsu, T, Toraya, T.
登録日2011-02-07
公開日2012-02-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Redesign of coenzyme B(12) dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols
Febs J., 279, 2012
8BG9
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BU of 8bg9 by Molmil
Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta
分子名称: Amyloid-beta protein 40
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BG0
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BU of 8bg0 by Molmil
Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40
分子名称: Amyloid-beta precursor protein
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (1.99 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BFZ
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BU of 8bfz by Molmil
Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42
分子名称: Amyloid-beta precursor protein
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordberg, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
3B2G
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BU of 3b2g by Molmil
Leptolyngbya boryana Ferredoxin
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1
著者Kurisu, G, Hase, T.
登録日2011-08-01
公開日2012-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献A new structural insight into differential interaction of cyanobacterial and plant ferredoxins with nitrite reductase as revealed by NMR and X-ray crystallographic studies
J.Biochem., 151, 2012
3B2F
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BU of 3b2f by Molmil
Maize Ferredoxin 1
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, chloroplastic
著者Kurisu, G, Hase, T.
登録日2011-08-01
公開日2012-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A new structural insight into differential interaction of cyanobacterial and plant ferredoxins with nitrite reductase as revealed by NMR and X-ray crystallographic studies
J.Biochem., 151, 2012
2DCH
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BU of 2dch by Molmil
Crystal structure of archaeal intron-encoded homing endonuclease I-Tsp061I
分子名称: CHLORIDE ION, SULFATE ION, putative homing endonuclease
著者Nakayama, H, Tsuge, H, Shimamura, T, Miyano, M, Nomura, N, Sako, Y.
登録日2006-01-06
公開日2006-07-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure of a hyperthermophilic archaeal homing endonuclease, I-Tsp061I: contribution of cross-domain polar networks to thermostability.
J.Mol.Biol., 365, 2007
6Z2K
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BU of 6z2k by Molmil
The structure of the tetrameric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
登録日2020-05-16
公開日2020-07-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
6Z2J
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BU of 6z2j by Molmil
The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
登録日2020-05-16
公開日2020-07-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
3KGL
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BU of 3kgl by Molmil
Crystal structure of procruciferin, 11S globulin from Brassica napus
分子名称: Cruciferin, GLYCEROL, SULFATE ION
著者Tandang-Silvas, M.R, Mikami, B, Maruyama, N, Utsumi, S.
登録日2009-10-29
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.981 Å)
主引用文献Conservation and divergence on plant seed 11S globulins based on crystal structures.
Biochim.Biophys.Acta, 1804, 2010
7FH2
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BU of 7fh2 by Molmil
Crystal structure of the first bromodomain of BRD4 in complex with 16D10
分子名称: Bromodomain-containing protein 4, CHLORIDE ION, N-[2-[2-[(E)-3-(2,5-dimethoxyphenyl)prop-2-enoyl]-4,5-dimethoxy-phenyl]ethyl]ethanamide
著者Yokoyama, T, Hirasawa, N.
登録日2021-07-29
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.492 Å)
主引用文献A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins.
Biochem Pharmacol, 194, 2021

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件を2024-08-28に公開中

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