6KB6

X-ray structure of human PPARalpha ligand binding domain-tetradecylthioacetic acid (TTA) co-crystals obtained by delipidation and cross-seeding

Summary for 6KB6

Entry DOI	10.2210/pdb6kb6/pdb
Descriptor	Peroxisome proliferator-activated receptor alpha, GLYCEROL, 2-tetradecylsulfanylethanoic acid, ... (4 entities in total)
Functional Keywords	nuclear receptor, protein-ligand complex, ppar, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	31236.64
Authors	Kamata, S.,Saito, K.,Honda, A.,Ishikawa, R.,Oyama, T.,Ishii, I. (deposition date: 2019-06-24, release date: 2020-11-11, Last modification date: 2023-11-22)
Primary citation	Kamata, S.,Oyama, T.,Saito, K.,Honda, A.,Yamamoto, Y.,Suda, K.,Ishikawa, R.,Itoh, T.,Watanabe, Y.,Shibata, T.,Uchida, K.,Suematsu, M.,Ishii, I. PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates. Iscience, 23:101727-101727, 2020 Cited by PubMed: 33205029 DOI: 10.1016/j.isci.2020.101727 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.431 Å)

Structure validation