8HQV
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8HQW
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8HR0
| The complex structure of COPII coat with HCoV-OC43 DD sorting motif | 分子名称: | HCoV-OC43, Protein transport protein Sec23A, Protein transport protein Sec24A, ... | 著者 | Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q. | 登録日 | 2022-12-14 | 公開日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations To Be Published
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7L0F
| Monobody 12VC3 Bound to HRAS(WT) | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... | 著者 | Teng, K.W, Hattori, T, Tsai, S, Koide, S. | 登録日 | 2020-12-11 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021
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7L0G
| Monobody 12VC1 Bound to HRAS(G12C) | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... | 著者 | Teng, K.W, Hattori, T, Tsai, S, Koide, S. | 登録日 | 2020-12-11 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021
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5ZF2
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8G9S
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | AcrIC8, Cas11, Cas5, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8G9T
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | AcrIC9, Cas11, Cas5, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8G9U
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | CRISPR-associated protein, Csd1 family, Csd2 family, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8GAF
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | Cas11, Cas5, Cas7, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8GAM
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | Cas11, Cas5, Cas7, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-23 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8GAN
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | Cas11, Cas5, Cas7, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-23 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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7K7T
| Crystal structure of human MORC4 ATPase-CW in complex with AMPPNP | 分子名称: | Isoform 3 of MORC family CW-type zinc finger protein 4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Klein, B.J, Tencer, A.H, Kutateladze, T.G. | 登録日 | 2020-09-24 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Molecular mechanism of the MORC4 ATPase activation. Nat Commun, 11, 2020
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8GYN
| zebrafish TIPE1 strucutre in complex with PE | 分子名称: | Tumor necrosis factor alpha-induced protein 8-like protein 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Wang, W, Cao, S.J. | 登録日 | 2022-09-23 | 公開日 | 2023-04-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Structural insight into TIPE1 functioning as a lipid transfer protein. J.Biomol.Struct.Dyn., 41, 2023
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7DRI
| Structure of SspE_CTD_41658 | 分子名称: | DUF1524 domain | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-28 | 公開日 | 2022-06-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRS
| Structure of SspE_40224 | 分子名称: | SspE protein | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-29 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRR
| Structure of SspE-R100A protein | 分子名称: | SspE protein | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-29 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7K5I
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4KQE
| The mutant structure of the human glycyl-tRNA synthetase E71G | 分子名称: | GLYCEROL, Glycine--tRNA ligase | 著者 | Qin, X, Hao, Z, Tian, Q, Zhang, Z, Zhou, C, Xie, W. | 登録日 | 2013-05-15 | 公開日 | 2014-05-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.739 Å) | 主引用文献 | Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis J.Biol.Chem., 291, 2016
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3WSQ
| Structure of HER2 with an Fab | 分子名称: | Antibody Heavy Chain, Antibody Light Chain, Receptor tyrosine-protein kinase erbB-2 | 著者 | Fu, W.Y, Wang, Y.X, Zhou, L.J. | 登録日 | 2014-03-20 | 公開日 | 2015-03-25 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Insights into HER2 signaling from step-by-step optimization of anti-HER2 antibodies. MAbs, 6, 2014
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7DHX
| Crystal structure of SARS-CoV-2 RBD binding to pangolin ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ZINC ION, ... | 著者 | Wang, Q.H, Qi, J.X, Wu, L.L. | 登録日 | 2020-11-17 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis of pangolin ACE2 engaged by COVID-19 virus Chin.Sci.Bull., 66, 2021
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4IAN
| Crystal Structure of apo Human PRPF4B kinase domain | 分子名称: | SULFATE ION, Serine/threonine-protein kinase PRP4 homolog | 著者 | Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. | 登録日 | 2012-12-06 | 公開日 | 2013-08-28 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches. J.Biol.Chem., 288, 2013
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3WYI
| Structure of S. aureus undecaprenyl diphosphate synthase | 分子名称: | Isoprenyl transferase, MAGNESIUM ION | 著者 | Gao, J, Ko, T.P, Huang, C.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-08-29 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Antibacterial drug leads: DNA and enzyme multitargeting. J.Med.Chem., 58, 2015
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3WYJ
| Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-789 | 分子名称: | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), [1-oxidanyl-2-[3-[3-[[3-[[3-[3-(2-oxidanyl-2,2-diphosphono-ethyl)phenyl]phenyl]sulfamoyl]phenyl]sulfonylamino]phenyl]phenyl]-1-phosphono-ethyl]phosphonic acid | 著者 | Gao, J, Ko, T.P, Huang, C.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-08-29 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Antibacterial drug leads: DNA and enzyme multitargeting. J.Med.Chem., 58, 2015
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5Y87
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