3WYJ

Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-789

Summary for 3WYJ

• Entry DOI: 10.2210/pdb3wyj/pdb
• Related: 3WYI
• Descriptor: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), [1-oxidanyl-2-[3-[3-[[3-[[3-[3-(2-oxidanyl-2,2-diphosphono-ethyl)phenyl]phenyl]sulfamoyl]phenyl]sulfonylamino]phenyl]phenyl]-1-phosphono-ethyl]phosphonic acid (3 entities in total)
• Functional Keywords: transferase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 2
• Total formula weight: 57910.93

Authors

Gao, J.,Ko, T.P.,Huang, C.H.,Oldfield, E.,Guo, R.T. (deposition date: 2014-08-29, release date: 2015-02-04, Last modification date: 2023-11-08)

• Primary citation: Zhu, W.,Wang, Y.,Li, K.,Gao, J.,Huang, C.H.,Chen, C.C.,Ko, T.P.,Zhang, Y.,Guo, R.T.,Oldfield, E.; Antibacterial drug leads: DNA and enzyme multitargeting.; J.Med.Chem., 58:1215-1227, 2015; PubMed: 25574764; DOI: 10.1021/jm501449u

Experimental method

X-RAY DIFFRACTION (2.1 Å)