4OJN
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4OKN
| Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, KANAMYCIN A, L-lactate dehydrogenase A chain, ... | 著者 | Kolappan, S, Craig, L. | 登録日 | 2014-01-22 | 公開日 | 2014-12-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. Acta Crystallogr.,Sect.D, 71, 2015
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4QT0
| Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 1, 3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL)QUINOLIN-4-YL]AMINO}BENZOIC ACID | 分子名称: | 3-{[3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino}benzoic acid, L-lactate dehydrogenase A chain | 著者 | Kolappan, S, Craig, L. | 登録日 | 2014-07-06 | 公開日 | 2014-12-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. Acta Crystallogr.,Sect.D, 71, 2015
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4QSM
| Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid | 分子名称: | 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid, L-lactate dehydrogenase A chain | 著者 | Kolappan, S, Craig, L. | 登録日 | 2014-07-06 | 公開日 | 2014-12-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. Acta Crystallogr.,Sect.D, 71, 2015
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5UJ8
| Human Origin Recognition Complex subunits 2 and 3 | 分子名称: | Origin recognition complex subunit 2, Origin recognition complex subunit 3 | 著者 | Tocilj, A, On, K.F, Elkayam, E, Joshua-Tor, L. | 登録日 | 2017-01-17 | 公開日 | 2017-02-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (6 Å) | 主引用文献 | Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
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5W6V
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5UJ7
| Structure of the active form of human Origin Recognition Complex ATPase motor module, complex subunitS 1, 4, 5 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ... | 著者 | Tocilj, A, Elkayam, E, On, K.F, Joshua-Tor, L. | 登録日 | 2017-01-17 | 公開日 | 2017-02-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.394 Å) | 主引用文献 | Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
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7CMZ
| Crystal Structure of BRCT7/8 in Complex with the APS Motif of PHF8 | 分子名称: | DNA topoisomerase 2-binding protein 1, Histone lysine demethylase PHF8, POTASSIUM ION, ... | 著者 | Che, S.Y, Ma, S, Cao, C, Yao, Z, Shi, L, Yang, N. | 登録日 | 2020-07-29 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.695 Å) | 主引用文献 | PHF8-promoted TOPBP1 demethylation drives ATR activation and preserves genome stability. Sci Adv, 7, 2021
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7CDI
| Crystal structure of SARS-CoV-2 antibody P2C-1F11 with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ... | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R. | 登録日 | 2020-06-19 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry. Nat Commun, 12, 2021
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7CDJ
| Crystal structure of SARS-CoV-2 antibody P2C-1A3 with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1A3 heavy chain, ... | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R. | 登録日 | 2020-06-19 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.396 Å) | 主引用文献 | Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry. Nat Commun, 12, 2021
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1L2J
| Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol | 分子名称: | (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, ESTROGEN RECEPTOR BETA | 著者 | Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L. | 登録日 | 2002-02-21 | 公開日 | 2002-05-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat.Struct.Biol., 9, 2002
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8INB
| Cryo-EM structure of Cas12j-SF05-crRNA-dsDNA complex | 分子名称: | Cas12j-SF05, NTS-DNA, TS-DNA, ... | 著者 | Zhang, X, Duan, Z.Q, Zhu, J.K. | 登録日 | 2023-03-09 | 公開日 | 2024-03-13 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05. Cell Discov, 9, 2023
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8JF3
| C-Src in complex with compound 9 | 分子名称: | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide, Proto-oncogene tyrosine-protein kinase Src | 著者 | Zhang, Z.M, Huang, H.S. | 登録日 | 2023-05-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.84647632 Å) | 主引用文献 | Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development. Angew.Chem.Int.Ed.Engl., 63, 2024
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8JF4
| The crystal structure of human AURKA kinase domain in complex with AURKA-compound 9 | 分子名称: | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide, Aurora kinase A | 著者 | Zhu, C.J. | 登録日 | 2023-05-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.89288354 Å) | 主引用文献 | Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development. Angew.Chem.Int.Ed.Engl., 63, 2024
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8JG8
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7FAS
| VAR2CSA 3D7 ectodomain core region | 分子名称: | Erythrocyte membrane protein 1, PfEMP1 | 著者 | Wang, L, Zhaoning, W. | 登録日 | 2021-07-07 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum. Cell Discov, 7, 2021
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7FAP
| Structure of VAR2CSA-CSA 3D7 | 分子名称: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1 | 著者 | Wang, L, Wang, Z. | 登録日 | 2021-07-07 | 公開日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum. Cell Discov, 7, 2021
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1I2H
| CRYSTAL STRUCTURE ANALYSIS OF PSD-ZIP45(HOMER1C/VESL-1L)CONSERVED HOMER 1 DOMAIN | 分子名称: | PSD-ZIP45(HOMER-1C/VESL-1L) | 著者 | Irie, K, Nakatsu, T, Mitsuoka, K, Fujiyoshi, Y, Kato, H. | 登録日 | 2001-02-09 | 公開日 | 2002-05-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the Homer 1 Family Conserved Region Reveals the Interaction Between the EVH1 Domain and
Own Proline-rich Motif J.Mol.Biol., 318, 2002
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7V56
| Structure of AdaV | 分子名称: | AdaV, FE (III) ION | 著者 | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V52
| Structure of AdaV | 分子名称: | AdaV, FE (III) ION | 著者 | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7VM8
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7V57
| Structure of AdaV | 分子名称: | 2-OXOGLUTARIC ACID, AdaV, CHLORIDE ION, ... | 著者 | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V54
| Structure of AdaV | 分子名称: | AdaV, FE (III) ION | 著者 | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V7X
| Structure of H194A AdaV | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, AdaV | 著者 | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | 登録日 | 2021-08-22 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7X98
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