5W6V

The Structure of human Argonaute-1 in complex with the hook motif of human GW182

Summary for 5W6V

• Entry DOI: 10.2210/pdb5w6v/pdb
• Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein, ... (4 entities in total)
• Functional Keywords: rna interference, rna binding proteins, gw motif, gene regulation-rna complex, gene regulation/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 103893.95

Authors

Elkayam, E.,Faehnle, C.R.,Joshua-Tor, L. (deposition date: 2017-06-17, release date: 2017-07-26, Last modification date: 2023-10-04)

• Primary citation: Elkayam, E.,Faehnle, C.R.,Morales, M.,Sun, J.,Li, H.,Joshua-Tor, L.; Multivalent Recruitment of Human Argonaute by GW182.; Mol. Cell, 67:646-658.e3, 2017; PubMed: 28781232; DOI: 10.1016/j.molcel.2017.07.007

Experimental method

X-RAY DIFFRACTION (2.828 Å)