5W6V
The Structure of human Argonaute-1 in complex with the hook motif of human GW182
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein argonaute-1 | polymer | 859 | 97477.4 | 1 | UniProt (Q9UL18) Pfam (PF16486) Pfam (PF08699) Pfam (PF02170) Pfam (PF16488) Pfam (PF16487) Pfam (PF02171) | Homo sapiens (Human) | hAgo1, Argonaute RISC catalytic component 1, Eukaryotic translation initiation factor 2C 1, eIF2C 1, RNA-binding protein Q99 |
| 2 | B (R) | RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3') | polymer | 20 | 4029.0 | 1 | Spodoptera frugiperda (fall armyworm) | ||
| 3 | C (B) | Trinucleotide repeat-containing gene 6A protein | polymer | 24 | 2387.5 | 1 | UniProt (Q8NDV7) | Homo sapiens (Human) | CAG repeat protein 26, EMSY interactor protein, GW182 autoantigen, Protein GW1, Glycine-tryptophan protein of 182 kDa |
| 4 | D, E (A, R) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 857 (UniProt: Q9UL18)
B: 820 - 841 (UniProt: Q8NDV7)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 818 | - | expression tag |
| Ala 819 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 103893.9 | |
| All* | Total formula weight | 103893.9 |
