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4OKN

Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate

Summary for 4OKN
Entry DOI10.2210/pdb4okn/pdb
Related4OJN
DescriptorL-lactate dehydrogenase A chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXALATE ION, ... (6 entities in total)
Functional Keywordsrossmann fold, nadh/nad+ cofactor, oxidoreductase-antibiotic complex, oxidoreductase/antibiotic
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P00338
Total number of polymer chains8
Total formula weight306170.06
Authors
Kolappan, S.,Craig, L. (deposition date: 2014-01-22, release date: 2014-12-03, Last modification date: 2024-02-28)
Primary citationKolappan, S.,Shen, D.L.,Mosi, R.,Sun, J.,McEachern, E.J.,Vocadlo, D.J.,Craig, L.
Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Acta Crystallogr.,Sect.D, 71:185-195, 2015
Cited by
PubMed: 25664730
DOI: 10.1107/S1399004714024791
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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