4OKN

Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	L-lactate dehydrogenase A chain	polymer	337	37432.3	8	UniProt (P00338) Pfam (PF00056) Pfam (PF02866) In PDB	Homo sapiens (human)	L-lactate dehydrogenase M chain, LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59
2	G, H, A, C, D...	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	7	Chemie (NAI)
3	G, H, A, B, C...	OXALATE ION	non-polymer		88.0	8	Chemie (OXL)
4	F, G, H, A, B...	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
5	B	KANAMYCIN A	non-polymer		484.5	1	Chemie (KAN)
6		water	water		18.0	775	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 2 - 332 (UniProt: P00338)

PDB	External Database	Details
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	299458.8
Non-Polymers*	Number of molecules	25
	Total formula weight	6711.3
All*	Total formula weight	306170.1

*Water molecules are not included.