7WRV
 
 | | The interface of JMB2002 Fab binds to SARS-CoV-2 Omicron Variant S | | 分子名称: | JMB2002 Fab heavy chain, JMB2002 Fab light chain, Spike glycoprotein | | 著者 | Yin, W, Xu, Y, Xu, P, Cao, X, Wu, C, Gu, C, He, X, Wang, X, Huang, S, Yuan, Q, Wu, K, Hu, W, Huang, Z, Liu, J, Wang, Z, Jia, F, Xia, K, Liu, P, Wang, X, Song, B, Zheng, J, Jiang, H, Cheng, X, Jiang, Y, Deng, S.J, Xu, H.E. | | 登録日 | 2022-01-27 | | 公開日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | | 主引用文献 | Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody.
Science, 375, 2022
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5UD8
 | | Crystal Structure of Mutant Ig-like Domain | | 分子名称: | Triggering receptor expressed on myeloid cells 2 | | 著者 | Sudom, A, Min, X, Wang, Z. | | 登録日 | 2016-12-23 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
J. Biol. Chem., 293, 2018
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4PBD
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5UD7
 | | Crystal Structure of Wild-Type Ig-like Domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IODIDE ION, SULFATE ION, ... | | 著者 | Sudom, A, Min, X, Wang, Z. | | 登録日 | 2016-12-23 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.20002246 Å) | | 主引用文献 | Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
J. Biol. Chem., 293, 2018
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4IDV
 | | Crystal Structure of NIK with compound 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol (13V) | | 分子名称: | 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol, Mitogen-activated protein kinase kinase kinase 14 | | 著者 | Liu, J, Sudom, A, Wang, Z. | | 登録日 | 2012-12-13 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures
Bioorg.Med.Chem.Lett., 23, 2013
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4RMZ
 | | Crystal Structure of IRAK-4 | | 分子名称: | 3-nitro-N-[1-phenyl-5-(piperidin-1-ylmethyl)-1H-benzimidazol-2-yl]benzamide, Interleukin-1 receptor-associated kinase 4 | | 著者 | Johnstone, S, Sudom, A, Liu, J, Walker, N.P, Wang, Z. | | 登録日 | 2014-10-22 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper
To be Published
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4IDT
 | | Crystal Structure of NIK with 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine (T28) | | 分子名称: | 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine, Mitogen-activated protein kinase kinase kinase 14 | | 著者 | Liu, J, Sudom, A, Wang, Z. | | 登録日 | 2012-12-13 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures
Bioorg.Med.Chem.Lett., 23, 2013
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4PQD
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1N5U
 | | X-RAY STUDY OF HUMAN SERUM ALBUMIN COMPLEXED WITH HEME | | 分子名称: | MYRISTIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SERUM ALBUMIN | | 著者 | Wardell, M, Wang, Z, Ho, J.X, Robert, J, Ruker, F, Ruble, J, Carter, D.C. | | 登録日 | 2002-11-07 | | 公開日 | 2003-06-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Atomic Structure of Human Methemalbumin at 1.9 A
Biochem.Biophys.Res.Commun., 291, 2002
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5UJV
 | | Crystal structure of FePYR1 in complex with abscisic acid | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, PYR1 | | 著者 | Ren, Z, Wang, Z, Zhou, X.E, Hong, Y, Cao, M, Chan, Z, Liu, X, Shi, H, Xu, H.E, Zhu, J.-K. | | 登録日 | 2017-01-19 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure determination and activity manipulation of the turfgrass ABA receptor FePYR1.
Sci Rep, 7, 2017
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7JTW
 | | Crystal structure of RORgt with compound (4R)-6-[(2,5-dichloro-3-{[(2R,4R)-1-(cyclopentanecarbonyl)-2-methylpiperidin-4-yl]oxy}phenyl)amino]-6-oxo-4-phenylhexanoic acid | | 分子名称: | (4R)-6-[(2,5-dichloro-3-{[(2R,4R)-1-(cyclopentanecarbonyl)-2-methylpiperidin-4-yl]oxy}phenyl)amino]-6-oxo-4-phenylhexanoic acid, GLYCEROL, RAR-related orphan receptor C isoform a variant, ... | | 著者 | Min, X, Wang, Z. | | 登録日 | 2020-08-18 | | 公開日 | 2021-02-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of 6-Oxo-4-phenyl-hexanoic acid derivatives as ROR gamma t inverse agonists showing favorable ADME profile.
Bioorg.Med.Chem.Lett., 36, 2021
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6TYD
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7JR7
 | | Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | | 分子名称: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, Fab 11F4 heavy chain, ... | | 著者 | Huang, C.S, Yu, X, Min, X, Wang, Z, Zhang, H. | | 登録日 | 2020-08-11 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies
Commun Biol, 4, 2021
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2LSL
 | | Solution structure of the C-terminal domain of Tetrahymena telomerase protein p65 | | 分子名称: | Telomerase associated protein p65 | | 著者 | Singh, M, Wang, Z, Koo, B, Patel, A, Cascio, D, Collins, K, Feigon, J. | | 登録日 | 2012-05-01 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
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2L3E
 | | Solution structure of P2a-J2a/b-P2b of human telomerase RNA | | 分子名称: | 35-MER | | 著者 | Zhang, Q, Kim, N, Peterson, R.D, Wang, Z, Feigon, J. | | 登録日 | 2010-09-13 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Inaugural Article: Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2MNW
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7V5K
 | | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1) | | 分子名称: | 0722 H, 0722 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-17 | | 公開日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1)
to be published
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7V5J
 | | MERS S ectodomain trimer in complex with neutralizing antibody 0722(state 2) | | 分子名称: | 0722 H, 0722 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 0722(state 2)
to be published
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7V6N
 | | MERS S ectodomain trimer in complex with neutralizing antibody 111 state1 | | 分子名称: | 111 H, 111 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-20 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 111 state1
to be published
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7V6O
 | | MERS S ectodomain trimer in complex with neutralizing antibody 111 (state 2) | | 分子名称: | 111 H, 111 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-20 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (4.56 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 111 (state 2)
to be published
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7V3L
 | | MERS S ectodomain trimer in complex with neutralizing antibody 6516 | | 分子名称: | Spike glycoprotein, antibody H, antibody L | | 著者 | Wang, X, Zhao, J, Wang, Z, Wang, Y, Zeng, J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 6516
to be published
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6KTH
 | | Crystal structure of Juvenile hormone diol kinase JHDK-L2 from silkworm, Bombyx mori | | 分子名称: | CALCIUM ION, GLYCEROL, Juvenile hormone diol kinase | | 著者 | Zhang, Y.S, Xu, H.Y, Wang, Z, Zhang, L, Zhao, P, Guo, P.C. | | 登録日 | 2019-08-28 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori.
Int.J.Biol.Macromol., 167, 2021
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8HUD
 | | Cryo-EM structure of the EvCas9-sgRNA-target DNA ternary complex | | 分子名称: | CRISPR-associated endonuclease Cas9, Non-target DNA strand, Target DNA strand, ... | | 著者 | Tang, N, Wu, Z, Gao, Y, Chen, W, Su, M, Wang, Z, Ji, Q. | | 登録日 | 2022-12-23 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | Molecular Basis and Genome Editing Applications of a Compact Eubacterium ventriosum CRISPR-Cas9 System.
Acs Synth Biol, 13, 2024
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6LJG
 | | Crassostrea gigas ferritin mutant-D119G | | 分子名称: | FE (III) ION, Ferritin | | 著者 | Li, H, Zang, J, Tan, X, Wang, Z, Du, M. | | 登録日 | 2019-12-15 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | | 主引用文献 | Crassostrea gigas ferritin mutant-D119G
To Be Published
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6LIJ
 | | Crassostrea gigas ferritin | | 分子名称: | Ferritin, MAGNESIUM ION | | 著者 | Li, H, Zang, J, Tan, X, Wang, Z, Du, M. | | 登録日 | 2019-12-11 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crassostrea gigas ferritin
To Be Published
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