7WRV

The interface of JMB2002 Fab binds to SARS-CoV-2 Omicron Variant S

Summary for 7WRV

• Entry DOI: 10.2210/pdb7wrv/pdb
• EMDB information: 32736
• Descriptor: Spike glycoprotein, JMB2002 Fab heavy chain, JMB2002 Fab light chain (3 entities in total)
• Functional Keywords: sars-cov-2, omicron, fab, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 3
• Total formula weight: 182519.04

Authors

Yin, W.,Xu, Y.,Xu, P.,Cao, X.,Wu, C.,Gu, C.,He, X.,Wang, X.,Huang, S.,Yuan, Q.,Wu, K.,Hu, W.,Huang, Z.,Liu, J.,Wang, Z.,Jia, F.,Xia, K.,Liu, P.,Wang, X.,Song, B.,Zheng, J.,Jiang, H.,Cheng, X.,Jiang, Y.,Deng, S.J.,Xu, H.E. (deposition date: 2022-01-27, release date: 2022-03-23)

• Primary citation: Yin, W.,Xu, Y.,Xu, P.,Cao, X.,Wu, C.,Gu, C.,He, X.,Wang, X.,Huang, S.,Yuan, Q.,Wu, K.,Hu, W.,Huang, Z.,Liu, J.,Wang, Z.,Jia, F.,Xia, K.,Liu, P.,Wang, X.,Song, B.,Zheng, J.,Jiang, H.,Cheng, X.,Jiang, Y.,Deng, S.J.,Xu, H.E.; Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody.; Science, 375:1048-1053, 2022; PubMed: 35133176; DOI: 10.1126/science.abn8863

Experimental method

ELECTRON MICROSCOPY (2.47 Å)