5ESK
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![BU of 5esk by Molmil](/molmil-images/mine/5esk) | Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G464S mutant complexed with itraconazole | 分子名称: | 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2015-11-16 | 公開日 | 2016-11-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 62, 2018
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5ESL
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![BU of 5esl by Molmil](/molmil-images/mine/5esl) | Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) T322I mutant complexed with itraconazole | 分子名称: | 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2015-11-16 | 公開日 | 2016-11-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structures of lanosterol 14-alpha demethylase mutants. To Be Published
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5ESN
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![BU of 5esn by Molmil](/molmil-images/mine/5esn) | Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) T322I mutant structure | 分子名称: | Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2015-11-16 | 公開日 | 2016-11-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structures of lanosterol 14-alpha demethylase mutants. To Be Published
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5ESM
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![BU of 5esm by Molmil](/molmil-images/mine/5esm) | Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) T322I mutant complexed with fluconazole | 分子名称: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2015-11-16 | 公開日 | 2016-11-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of lanosterol 14-alpha demethylase mutants. To Be Published
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1BL5
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![BU of 1bl5 by Molmil](/molmil-images/mine/1bl5) | ISOCITRATE DEHYDROGENASE FROM E. COLI SINGLE TURNOVER LAUE STRUCTURE OF RATE-LIMITED PRODUCT COMPLEX, 10 MSEC TIME RESOLUTION | 分子名称: | 2-OXOGLUTARIC ACID, ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ... | 著者 | Stoddard, B.L, Cohen, B, Brubaker, M, Mesecar, A, Koshland Junior, D.E. | 登録日 | 1998-07-23 | 公開日 | 1999-05-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Millisecond Laue structures of an enzyme-product complex using photocaged substrate analogs. Nat.Struct.Biol., 5, 1998
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1CII
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![BU of 1cii by Molmil](/molmil-images/mine/1cii) | |
1CW7
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![BU of 1cw7 by Molmil](/molmil-images/mine/1cw7) | |
1CW4
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![BU of 1cw4 by Molmil](/molmil-images/mine/1cw4) | |
1CW1
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![BU of 1cw1 by Molmil](/molmil-images/mine/1cw1) | |
3INK
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![BU of 3ink by Molmil](/molmil-images/mine/3ink) | |
4KPW
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![BU of 4kpw by Molmil](/molmil-images/mine/4kpw) | |
5V5Z
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![BU of 5v5z by Molmil](/molmil-images/mine/5v5z) | Structure of CYP51 from the pathogen Candida albicans | 分子名称: | 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Keniya, M.V, Sabherwal, M, Wilson, R.K, Sagatova, A.A, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2017-03-15 | 公開日 | 2017-03-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structures of Full-Length Lanosterol 14 alpha-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provide Tools for Antifungal Discovery. Antimicrob.Agents Chemother., 62, 2018
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3B7D
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![BU of 3b7d by Molmil](/molmil-images/mine/3b7d) | |
4O1X
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![BU of 4o1x by Molmil](/molmil-images/mine/4o1x) | |
1TYS
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![BU of 1tys by Molmil](/molmil-images/mine/1tys) | |
4O1U
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![BU of 4o1u by Molmil](/molmil-images/mine/4o1u) | |
5JLC
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![BU of 5jlc by Molmil](/molmil-images/mine/5jlc) | Structure of CYP51 from the pathogen Candida glabrata | 分子名称: | 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, CHLORIDE ION, Lanosterol 14-alpha demethylase, ... | 著者 | Keniya, M.V, Sabherwal, M, Wilson, R.K, Sagatova, A.A, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2016-04-26 | 公開日 | 2016-05-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of Full-Length Lanosterol 14 alpha-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provide Tools for Antifungal Discovery. Antimicrob.Agents Chemother., 62, 2018
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1LS1
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![BU of 1ls1 by Molmil](/molmil-images/mine/1ls1) | |
1C1T
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![BU of 1c1t by Molmil](/molmil-images/mine/1c1t) | |
1C2L
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1C1P
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![BU of 1c1p by Molmil](/molmil-images/mine/1c1p) | |
1C2M
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![BU of 1c2m by Molmil](/molmil-images/mine/1c2m) | |
1C1N
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![BU of 1c1n by Molmil](/molmil-images/mine/1c1n) | |
1C1W
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![BU of 1c1w by Molmil](/molmil-images/mine/1c1w) | |
1C2H
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![BU of 1c2h by Molmil](/molmil-images/mine/1c2h) | |