5ESM

Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) T322I mutant complexed with fluconazole

Summary for 5ESM

• Entry DOI: 10.2210/pdb5esm/pdb
• Related: 5ESE 5ESF 5ESG 5ESH 5ESI 5ESK 5ESL 5ESM 5ESN
• Descriptor: Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, ... (4 entities in total)
• Functional Keywords: cyp51, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
• Total number of polymer chains: 1
• Total formula weight: 62820.03

Authors

Sagatova, A.,Keniya, M.V.,Wilson, R.K.,Sabherwal, M.,Tyndall, J.D.A.,Monk, B.C. (deposition date: 2015-11-16, release date: 2016-11-23, Last modification date: 2023-09-27)

• Primary citation: Sagatova, A.,Keniya, M.V.,Wilson, R.K.,Sabherwal, M.,Tyndall, J.D.A.,Monk, B.C.; Structures of lanosterol 14-alpha demethylase mutants.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)