1TYS
WATER-MEDIATED SUBSTRATE(SLASH)PRODUCT DISCRIMINATION: THE PRODUCT COMPLEX OF THYMIDYLATE SYNTHASE AT 1.83 ANGSTROMS
Summary for 1TYS
| Entry DOI | 10.2210/pdb1tys/pdb |
| Descriptor | THYMIDYLATE SYNTHASE, THYMIDINE-5'-PHOSPHATE, DIHYDROFOLIC ACID, ... (4 entities in total) |
| Functional Keywords | transferase, methyltransferase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm: P00470 |
| Total number of polymer chains | 1 |
| Total formula weight | 31309.22 |
| Authors | Fauman, E.,Rutenber, E.,Stroud, R. (deposition date: 1993-05-07, release date: 1994-06-22, Last modification date: 2011-07-13) |
| Primary citation | Fauman, E.B.,Rutenber, E.E.,Maley, G.F.,Maley, F.,Stroud, R.M. Water-mediated substrate/product discrimination: the product complex of thymidylate synthase at 1.83 A. Biochemistry, 33:1502-1511, 1994 Cited by PubMed: 8312270DOI: 10.1021/bi00172a029 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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