1TYS
WATER-MEDIATED SUBSTRATE(SLASH)PRODUCT DISCRIMINATION: THE PRODUCT COMPLEX OF THYMIDYLATE SYNTHASE AT 1.83 ANGSTROMS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | THYMIDYLATE SYNTHASE | polymer | 264 | 30543.6 | 1 | UniProt (P00470) Pfam (PF00303) UniProt (by SIFTS) (P0A884) In PDB | Escherichia coli | |
2 | A | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) | |||
3 | A | DIHYDROFOLIC ACID | non-polymer | 443.4 | 1 | Chemie (DHF) | |||
4 | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A: 1 - 264 (UniProt: P00470)
PDB | External Database | Details |
---|---|---|
Ser 146 | Cys 146 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 30543.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 765.6 | |
All* | Total formula weight | 31309.2 |