1TYS
WATER-MEDIATED SUBSTRATE(SLASH)PRODUCT DISCRIMINATION: THE PRODUCT COMPLEX OF THYMIDYLATE SYNTHASE AT 1.83 ANGSTROMS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDYLATE SYNTHASE | polymer | 264 | 30543.6 | 1 | UniProt (P00470) Pfam (PF00303) UniProt (by SIFTS) (P0A884) | Escherichia coli | |
| 2 | B (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) | |||
| 3 | C (A) | DIHYDROFOLIC ACID | non-polymer | 443.4 | 1 | Chemie (DHF) | |||
| 4 | D (A) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A: 1 - 264 (UniProt: P00470)
| PDB | External Database | Details |
|---|---|---|
| Ser 146 | Cys 146 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30543.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 765.6 | |
| All* | Total formula weight | 31309.2 |
