1TYS
WATER-MEDIATED SUBSTRATE(SLASH)PRODUCT DISCRIMINATION: THE PRODUCT COMPLEX OF THYMIDYLATE SYNTHASE AT 1.83 ANGSTROMS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDYLATE SYNTHASE | polymer | 264 | 30543.6 | 1 | UniProt (P00470) Pfam (PF00303) UniProt (by SIFTS) (P0A884) | Escherichia coli | |
| 2 | B (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (444919) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (5748250) PubChem (9700) PubChem (10147784) PubChem (5274091) PubChem (129069890) PubChem (133126478) PubChem (164603144) | |||
| 3 | C (A) | DIHYDROFOLIC ACID | non-polymer | 443.4 | 1 | Chemie (DHF) | |||
| 4 | D (A) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A: 1 - 264 (UniProt: P00470)
| PDB | External Database | Details |
|---|---|---|
| Ser 146 | Cys 146 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30543.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 765.6 | |
| All* | Total formula weight | 31309.2 |
