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1VZ3
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BU of 1vz3 by Molmil
PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, T597C MUTANT
分子名称: GLYCEROL, PROLYL ENDOPEPTIDASE
著者Rea, D, Fulop, V.
登録日2004-05-14
公開日2004-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Concerted Structural Changes in the Peptidase and the Propeller Domains of Prolyl Oligopeptidase are Required for Substrate Binding
J.Mol.Biol., 340, 2004
2OM6
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BU of 2om6 by Molmil
Hypothetical Protein (Probable Phosphoserine Phosph (PH0253) from Pyrococcus Horikoshii OT3
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable phosphoserine phosphatase, ...
著者Jeyakanthan, J, Vaijayanthimala, S, Gayathri, D, Velmurugan, D, Baba, S, Ebihara, A, Shinkai, A, Kuramitsu, S, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-01-21
公開日2008-01-29
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Hypothetical Protein (Probable Phosphoserine Phosph (PH0253) from Pyrococcus Horikoshii OT3
To be Published
6VRL
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BU of 6vrl by Molmil
Cryo-EM structure of the wild-type human serotonin transporter complexed with I-paroxetine and 8B6 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ...
著者Coleman, J.A, Navratna, V, Yang, D.
登録日2020-02-07
公開日2020-03-11
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Chemical and structural investigation of the paroxetine-human serotonin transporter complex.
Elife, 9, 2020
7P9Q
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Crystal structure of Indole 3-Carboxylic acid decarboxylase from Arthrobacter nicotianae FI1612 in complex with co-factor prFMN.
分子名称: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, AnInD, MANGANESE (II) ION, ...
著者Gahloth, D, Leys, D.
登録日2021-07-27
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural and biochemical characterization of the prenylated flavin mononucleotide-dependent indole-3-carboxylic acid decarboxylase.
J.Biol.Chem., 298, 2022
6FKB
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BU of 6fkb by Molmil
Crystal structure of N2C/D282C stabilized opsin bound to RS13
分子名称: 2-(4-chlorophenyl)-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ...
著者Mattle, D, Standfuss, J, Dawson, R.
登録日2018-01-23
公開日2018-04-04
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FK6
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BU of 6fk6 by Molmil
Crystal structure of N2C/D282C stabilized opsin bound to RS01
分子名称: (2~{S})-2-(4-chlorophenyl)-3-methyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one, PALMITIC ACID, Rhodopsin, ...
著者Mattle, D, Standfuss, J, Dawson, R.
登録日2018-01-23
公開日2018-04-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6W32
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BU of 6w32 by Molmil
Crystal structure of Sfh5
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Phosphatidylinositol transfer protein SFH5
著者Gulten, G, Khan, D, Aggarwal, A, Krieger, I, Sacchettini, J.C, Bankaitis, V.A.
登録日2020-03-08
公開日2020-11-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins.
Elife, 9, 2020
7UHB
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BU of 7uhb by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, Spike glycoprotein
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-03-26
公開日2022-06-08
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
6FK8
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BU of 6fk8 by Molmil
Crystal structure of N2C/D282C stabilized opsin bound to RS08
分子名称: (2~{R},3~{S})-3-azanyl-2-(4-chlorophenyl)-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one, PALMITIC ACID, Rhodopsin, ...
著者Mattle, D, Standfuss, J, Dawson, R.
登録日2018-01-23
公開日2018-04-04
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FK7
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BU of 6fk7 by Molmil
Crystal structure of N2C/D282C stabilized opsin bound to RS06
分子名称: (2~{R},3~{R})-2-(4-chlorophenyl)-3-oxidanyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one, PALMITIC ACID, Rhodopsin, ...
著者Mattle, D, Standfuss, J, Dawson, R.
登録日2018-01-23
公開日2018-04-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FKD
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BU of 6fkd by Molmil
Crystal structure of N2C/D282C stabilized opsin bound to RS16
分子名称: 5-chloranyl-2-(2-oxidanylidene-2-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-ethyl)-3~{H}-pyridin-6-one, PALMITIC ACID, Rhodopsin, ...
著者Mattle, D, Standfuss, J, Dawson, R.
登録日2018-01-23
公開日2018-04-04
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6W2C
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BU of 6w2c by Molmil
Anomalous iodine signal reveals the position of I-paroxetine complexed with the serotonin transporter at the central site
分子名称: 8B6 heavy chain antibody fragment, 8B6 light chain antibody fragment, I-paroxetine, ...
著者Coleman, J.A, Navratna, V, Yang, D.
登録日2020-03-05
公開日2020-03-25
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (6.3 Å)
主引用文献Chemical and structural investigation of the paroxetine-human serotonin transporter complex.
Elife, 9, 2020
1W9M
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BU of 1w9m by Molmil
AS-isolated hybrid cluster protein from Desulfovibrio vulgaris X-ray structure at 1.35A resolution using iron anomalous signal
分子名称: FE-S-O HYBRID CLUSTER, HYDROXYLAMINE REDUCTASE, IRON/SULFUR CLUSTER
著者Aragao, D, Macedo, S, Mitchell, E.P, Coelho, D, Romao, C.V, Teixeira, M, Lindley, P.F.
登録日2004-10-14
公開日2005-02-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural and Functional Relationships in the Hybrid Cluster Protein Family:Structure of the Anaerobically Purified Hybrid Cluster Protein from Desulfovibrio Vulgaris at 1.35 A Resolution
Acta Crystallogr.,Sect.D, 64, 2008
6BQR
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BU of 6bqr by Molmil
Human TRPM4 ion channel in lipid nanodiscs in a calcium-free state
分子名称: CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 4
著者Autzen, H.E, Myasnikov, A.G, Campbell, M.G, Asarnow, D, Julius, D, Cheng, Y.
登録日2017-11-28
公開日2017-12-20
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the human TRPM4 ion channel in a lipid nanodisc.
Science, 359, 2018
9DGO
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BU of 9dgo by Molmil
Designed miniproteins potently inhibit and protect against MERS-CoV. Crystal structure of MERS-CoV S RBD in complex with miniprotein cb3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Designed miniprotein cb_3, ...
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-09-03
公開日2025-06-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Designed miniproteins potently inhibit and protect against MERS-CoV.
Cell Rep, 44, 2025
6BQV
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BU of 6bqv by Molmil
Human TRPM4 ion channel in lipid nanodiscs in a calcium-bound state
分子名称: CALCIUM ION, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 4
著者Autzen, H.E, Myasnikov, A.G, Campbell, M.G, Asarnow, D, Julius, D, Cheng, Y.
登録日2017-11-28
公開日2017-12-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the human TRPM4 ion channel in a lipid nanodisc.
Science, 359, 2018
6WZN
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BU of 6wzn by Molmil
Crystal Structure of a Fluorescent Single Chain Fv Chimera
分子名称: Fluorescent Single Chain Fv Chimera, GLYCEROL
著者Close, D, Velappan, N, Hung, L.W, Naranjo, L, Hemez, C, DeVore, N, McCullough, D, Lillo, A.M, Waldo, G, Bradbury, A.R.M.
登録日2020-05-14
公開日2021-01-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Construction, characterization and crystal structure of a fluorescent single-chain Fv chimera.
Protein Eng.Des.Sel., 34, 2021
2WBS
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BU of 2wbs by Molmil
Crystal structure of the zinc finger domain of Klf4 bound to its target DNA
分子名称: 5'-D(*GP*AP*GP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP*CP*TP*CP)-3', GLYCEROL, ...
著者Zocher, G, Schuetz, A, Carstanjen, D, Heinemann, U.
登録日2009-03-03
公開日2010-04-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
7K4N
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BU of 7k4n by Molmil
SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2E12 neutralizing antibody Fab fragment (heavy chain), ...
著者Tortorici, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-15
公開日2020-10-07
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 370, 2020
6SI8
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Escherichia coli AGPase in complex with AMP.
分子名称: ADENOSINE MONOPHOSPHATE, Glucose-1-phosphate adenylyltransferase
著者Cifuente, J.O, Comino, N, D'Angelo, C, Marina, A, Gil-Carton, D, Albesa-Jove, D, Guerin, M.E.
登録日2019-08-09
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM.
Curr Res Struct Biol, 2, 2020
6C2Q
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Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of the PLP-L-Serine Intermediate
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Kreinbring, C.A, Tu, Y, Liu, D, Petsko, G.A, Ringe, D.
登録日2018-01-08
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.
Biochemistry, 57, 2018
3BCM
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BU of 3bcm by Molmil
Crystal Structure of The Unswapped Form of P19A/L28Q/N67D BS-RNase
分子名称: PHOSPHATE ION, Seminal ribonuclease
著者Merlino, A, Ercole, C, Picone, D, Pizzo, E, Mazzarella, L, Sica, F.
登録日2007-11-13
公開日2008-02-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme
J.Mol.Biol., 376, 2008
7QTK
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BU of 7qtk by Molmil
SARS-CoV-2 S Omicron Spike B.1.1.529 - RBD down - 1-P2G3 Fab (Local)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2G3 Heavy Chain, P2G3 Light Chain, ...
著者Ni, D, Lau, K, Turelli, P, Fenwick, C, Perez, L, Pojer, F, Stahlberg, H, Pantaleo, G, Trono, D.
登録日2022-01-14
公開日2022-08-03
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys.
Nat Microbiol, 7, 2022
7QTI
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SARS-CoV-2 S Omicron Spike B.1.1.529 - 3-P2G3 and 1-P5C3 Fabs (Global)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2G3 Heavy Chain, ...
著者Ni, D, Lau, K, Turelli, P, Fenwick, C, Perez, L, Pojer, F, Stahlberg, H, Pantaleo, G, Trono, D.
登録日2022-01-14
公開日2022-08-03
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys.
Nat Microbiol, 7, 2022
7QTJ
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SARS-CoV-2 S Omicron Spike B.1.1.529 - RBD up - 1-P2G3 and 1-P5C3 Fabs (Local)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2G3 Heavy Chain, P2G3 Light Chain, ...
著者Ni, D, Lau, K, Turelli, P, Fenwick, C, Perez, L, Pojer, F, Stahlberg, H, Pantaleo, G, Trono, D.
登録日2022-01-14
公開日2022-08-03
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.01 Å)
主引用文献Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys.
Nat Microbiol, 7, 2022

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