2WBS

Crystal structure of the zinc finger domain of Klf4 bound to its target DNA

Summary for 2WBS

• Entry DOI: 10.2210/pdb2wbs/pdb
• Related: 2WBU
• Descriptor: KRUEPPEL-LIKE FACTOR 4, 5'-D(*GP*AP*GP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP*CP*TP*CP)-3', ... (6 entities in total)
• Functional Keywords: transcription-dna complex, dna-binding, transcription, metal-binding, dna, protein, nucleus, activator, zinc-finger, transcription regulation, transcription/dna
• Biological source: MUS MUSCULUS (MOUSE); More
• Cellular location: Nucleus: Q60793
• Total number of polymer chains: 3
• Total formula weight: 15084.12

Authors

Zocher, G.,Schuetz, A.,Carstanjen, D.,Heinemann, U. (deposition date: 2009-03-03, release date: 2010-04-07, Last modification date: 2024-05-08)

• Primary citation: Schuetz, A.,Nana, D.,Rose, C.,Zocher, G.,Milanovic, M.,Koenigsmann, J.,Blasig, R.,Heinemann, U.,Carstanjen, D.; The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.; Cell.Mol.Life Sci., 68:3121-, 2011; PubMed: 21290164; DOI: 10.1007/S00018-010-0618-X

Experimental method

X-RAY DIFFRACTION (1.7 Å)