6C2Q

Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of the PLP-L-Serine Intermediate

Summary for 6C2Q

Entry DOI	10.2210/pdb6c2q/pdb
Related	6C2H 6C2Z
Descriptor	Cystathionine beta-synthase, L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene], CALCIUM ION, ... (9 entities in total)
Functional Keywords	cbs, synthase, plp, lyase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	1
Total formula weight	42417.25
Authors	Kreinbring, C.A.,Tu, Y.,Liu, D.,Petsko, G.A.,Ringe, D. (deposition date: 2018-01-08, release date: 2018-04-25, Last modification date: 2023-10-04)
Primary citation	Tu, Y.,Kreinbring, C.A.,Hill, M.,Liu, C.,Petsko, G.A.,McCune, C.D.,Berkowitz, D.B.,Liu, D.,Ringe, D. Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time. Biochemistry, 57:3134-3145, 2018 Cited by PubMed: 29630349 DOI: 10.1021/acs.biochem.8b00092 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.17 Å)

Structure validation