1B7I
 
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 K61R | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-30 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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1B7K
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 R47H | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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1QPE
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1QPJ
 | | CRYSTAL STRUCTURE OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH STAUROSPORINE. | | 分子名称: | LCK TYROSINE KINASE, STAUROSPORINE, SULFATE ION | | 著者 | Zhu, X, Kim, J.L, Rose, P.E, Stover, D.R, Toledo, L.M. | | 登録日 | 1999-05-25 | | 公開日 | 2000-05-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
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5COS
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8AME
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N14SA16H | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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5D7X
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5E73
 | | Crystal Structure of BAZ2B bromodomain in complex with acetylindole compound UZH47 | | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2B, N-(1-acetyl-1H-indol-3-yl)-N-(5-hydroxy-2-methylphenyl)acetamide | | 著者 | Lolli, G, Spiliotopoulos, D, Unzue, A, Nevado, C, Caflisch, A. | | 登録日 | 2015-10-11 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | The "Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains.
J. Med. Chem., 59, 2016
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1XX2
 | | Refinement of P99 beta-lactamase from Enterobacter cloacae | | 分子名称: | Beta-lactamase | | 著者 | Knox, J.R, Sun, T. | | 登録日 | 2004-11-03 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog.
Biochemistry, 33, 1994
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5E74
 | | Crystal Structure of BAZ2B bromodomain in complex with acetylindole compound UZH50 | | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2B, N-(1-acetyl-1H-indol-3-yl)-N-(5-hydroxy-2-methylphenyl)-3-(trifluoromethyl)benzamide | | 著者 | Lolli, G, Spiliotopoulos, D, Dolbois, A, Nevado, C, Caflisch, A. | | 登録日 | 2015-10-11 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.783 Å) | | 主引用文献 | The "Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains.
J. Med. Chem., 59, 2016
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5CAM
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3QQU
 | | Cocrystal structure of unphosphorylated igf with pyrimidine 8 | | 分子名称: | Insulin-like growth factor 1 receptor, N~2~-[3-methoxy-4-(morpholin-4-yl)phenyl]-N~4~-(quinolin-3-yl)pyrimidine-2,4-diamine | | 著者 | Huang, X. | | 登録日 | 2011-02-16 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
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2MSJ
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N46S | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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3PTE
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7EEV
 | | Structure of UTP cyclohydrolase | | 分子名称: | DEOXYURIDINE-5'-TRIPHOSPHATE, GTP cyclohydrolase II, ZINC ION | | 著者 | Zhang, H, Zhang, Y, Yuchi, Z. | | 登録日 | 2021-03-19 | | 公開日 | 2021-07-28 | | 最終更新日 | 2022-09-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural and biochemical investigation of UTP cyclohydrolase
Acs Catalysis, 2021
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3SEK
 | | Crystal Structure of the Myostatin:Follistatin-like 3 Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Follistatin-related protein 3, Growth/differentiation factor 8 | | 著者 | Cash, J.N, Thompson, T.B. | | 登録日 | 2011-06-10 | | 公開日 | 2011-11-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structure of myostatinfollistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding.
J.Biol.Chem., 287, 2012
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7EJ3
 | | UTP cyclohydrolase | | 分子名称: | DIPHOSPHATE, GLYCINE, GTP cyclohydrolase II, ... | | 著者 | Zhang, H, Zhang, Y, Yuchi, Z. | | 登録日 | 2021-04-01 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and biochemical investigation of UTP cyclohydrolase
Acs Catalysis, 2021
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3SMA
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1BLS
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5GTR
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1A5V
 | | ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3 AND MN CATION | | 分子名称: | 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE, MANGANESE (II) ION | | 著者 | Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A. | | 登録日 | 1998-02-18 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
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4P5Z
 | | Human EphA3 Kinase domain in complex with quinoxaline derivatives | | 分子名称: | 2-amino-1-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide, Ephrin type-A receptor 3 | | 著者 | Dong, J, Caflisch, A. | | 登録日 | 2014-03-20 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Pyrrolo[3,2-b]quinoxaline Derivatives as Types I1/2 and II Eph Tyrosine Kinase Inhibitors: Structure-Based Design, Synthesis, and in Vivo Validation.
J.Med.Chem., 57, 2014
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1A5X
 | | ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3 | | 分子名称: | 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE | | 著者 | Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A. | | 登録日 | 1998-02-18 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
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4P5Q
 | | Human EphA3 Kinase domain in complex with quinoxaline derivatives | | 分子名称: | 2-amino-1-(2-chlorophenyl)-N-(3-ethoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide, Ephrin type-A receptor 3 | | 著者 | Dong, J, Caflisch, A. | | 登録日 | 2014-03-19 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Pyrrolo[3,2-b]quinoxaline Derivatives as Types I1/2 and II Eph Tyrosine Kinase Inhibitors: Structure-Based Design, Synthesis, and in Vivo Validation.
J.Med.Chem., 57, 2014
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4P4C
 | | Human EphA3 Kinase domain in complex with quinoxaline derivatives | | 分子名称: | 2-amino-1-(3-methoxyphenyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide, EPH receptor A3 | | 著者 | Dong, J, Caflisch, A. | | 登録日 | 2014-03-12 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Pyrrolo[3,2-b]quinoxaline Derivatives as Types I1/2 and II Eph Tyrosine Kinase Inhibitors: Structure-Based Design, Synthesis, and in Vivo Validation.
J.Med.Chem., 57, 2014
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