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6WPH
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BU of 6wph by Molmil
Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and (-)-FTC
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA Primer 21-mer, DNA template 27-mer, ...
著者Bertoletti, N, Anderson, K.S.
登録日2020-04-27
公開日2020-11-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance.
Molecules, 25, 2020
8G93
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BU of 8g93 by Molmil
Crystal structures of 17-beta-hydroxysteroid dehydrogenase 13
分子名称: 3-fluoro-N-({(1r,4r)-4-[(2-fluorophenoxy)methyl]-1-hydroxycyclohexyl}methyl)-4-hydroxybenzamide, Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Liu, S.
登録日2023-02-21
公開日2023-08-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13.
Nat Commun, 14, 2023
8G9V
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BU of 8g9v by Molmil
Crystal structures of 17-beta-hydroxysteroid dehydrogenase 13
分子名称: 17-beta-hydroxysteroid dehydrogenase 13, 4-{[2,5-dimethyl-3-(4-methylbenzene-1-sulfonyl)benzene-1-sulfonyl]amino}benzoic acid, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Liu, S.
登録日2023-02-22
公開日2023-08-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13.
Nat Commun, 14, 2023
8G84
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BU of 8g84 by Molmil
Crystal structures of HSD17B13 complexes
分子名称: Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Liu, S.
登録日2023-02-17
公開日2023-08-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.467 Å)
主引用文献Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13.
Nat Commun, 14, 2023
8G89
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BU of 8g89 by Molmil
HSD17B13 in complex with cofactor and inhibitor
分子名称: 3-fluoro-N-({(1r,4r)-4-[(2-fluorophenoxy)methyl]-1-hydroxycyclohexyl}methyl)-4-hydroxybenzamide, Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Liu, S.
登録日2023-02-17
公開日2023-08-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.222 Å)
主引用文献Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13.
Nat Commun, 14, 2023
6XFT
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BU of 6xft by Molmil
Crystal Structure of the Cys-NO Modified YopH Tyrosine Phosphatase
分子名称: Tyrosine-protein phosphatase YopH
著者Fernandes, R, Pereira, H.M, Thiemann, O, Terenzi, H.
登録日2020-06-16
公開日2021-06-23
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structure of the Cys-NO modified YopH tyrosine phosphatase.
Biochim Biophys Acta Proteins Proteom, 1870, 2022
6WPF
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BU of 6wpf by Molmil
Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and d4T
分子名称: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA Primer 21-mer, DNA template 27-mer, ...
著者Bertoletti, N, Anderson, K.S.
登録日2020-04-27
公開日2020-11-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance.
Molecules, 25, 2020
3OYA
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BU of 3oya by Molmil
Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and raltegravir at 2.65 resolution
分子名称: AMMONIUM ION, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ...
著者Hare, S, Cherepanov, P.
登録日2010-09-23
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.
Proc.Natl.Acad.Sci.USA, 107, 2010
1M07
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BU of 1m07 by Molmil
RESIDUES INVOLVED IN THE CATALYSIS AND BASE SPECIFICITY OF CYTOTOXIC RIBONUCLEASE FROM BULLFROG (RANA CATESBEIANA)
分子名称: 5'-D(*AP*CP*GP*A)-3', Ribonuclease
著者Leu, Y.-J, Chern, S.-S, Wang, S.-C, Hsiao, Y.-Y, Amiraslanov, I, Liaw, Y.-C, Liao, Y.-D.
登録日2002-06-12
公開日2003-01-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography
J.Biol.Chem., 278, 2003
1KPT
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BU of 1kpt by Molmil
STRUCTURE AND FUNCTION OF A VIRALLY ENCODED FUNGAL TOXIN FROM USTILAGO MAYDIS: A FUNGAL AND MAMMALIAN CALCIUM CHANNEL INHIBITOR
分子名称: KP4 TOXIN
著者Gu, F, Smith, T.
登録日1995-06-06
公開日1995-10-31
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and function of a virally encoded fungal toxin from Ustilago maydis: a fungal and mammalian Ca2+ channel inhibitor.
Structure, 3, 1995
8BZO
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BU of 8bzo by Molmil
Cryo-EM structure of CDK2-CyclinA in complex with p27 from the SCFSKP2 E3 ligase Complex
分子名称: Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B
著者Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.
登録日2022-12-15
公開日2023-06-28
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
8BYA
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BU of 8bya by Molmil
Cryo-EM structure of SKP1-SKP2-CKS1-CDK2-CyclinA-p27KIP1 Complex
分子名称: Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, ...
著者Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.
登録日2022-12-12
公開日2023-06-28
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
8BYL
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BU of 8byl by Molmil
Cryo-EM structure of SKP1-SKP2-CKS1 from the SCFSKP2 E3 ligase complex
分子名称: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, S-phase kinase-associated protein 1, ...
著者Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.M.
登録日2022-12-13
公開日2023-06-28
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
8B4U
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BU of 8b4u by Molmil
The crystal structure of PET46, a PETase enzyme from Candidatus bathyarchaeota
分子名称: 1,2-ETHANEDIOL, Alpha/beta hydrolase, CHLORIDE ION, ...
著者Costanzi, E, Applegate, V, Schumacher, J, Smits, S.H.J.
登録日2022-09-21
公開日2023-08-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate.
Commun Chem, 6, 2023
8T52
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BU of 8t52 by Molmil
HIV-1 Integrase Catalytic Core Domain (CCD) F185H/Y99H/A128T Mutant Complexed with EKC-110
分子名称: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,6-dimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase
著者Dinh, T, Kvaratskhelia, M.
登録日2023-06-12
公開日2024-06-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
Biorxiv, 2024
8T5B
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BU of 8t5b by Molmil
HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor EKC-110
分子名称: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,6-dimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase, MAGNESIUM ION
著者Dinh, T, Kvaratskhelia, M.
登録日2023-06-12
公開日2024-06-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
Biorxiv, 2024
8T5A
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BU of 8t5a by Molmil
HIV-1 Integrase Catalytic Core Domain (CCD) F185H/Y99H/A128T Mutant Complexed with STP03-0404
分子名称: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase
著者Dinh, T, Kvaratskhelia, M.
登録日2023-06-12
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
Biorxiv, 2024
8S9Q
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BU of 8s9q by Molmil
HIV-1 Integrase Catalytic Core Domain (CCD) F185H Mutant Complexed with STP03-0404
分子名称: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase
著者Dinh, T, Kvaratskhelia, M.
登録日2023-03-29
公開日2024-02-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
Biorxiv, 2024
8D3S
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BU of 8d3s by Molmil
HIV-1 Integrase Catalytic Core Domain F185H Mutant Complexed with BKC-110
分子名称: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,6-dimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase
著者Dinh, T, Kvaratskhelia, M.
登録日2022-06-01
公開日2023-06-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
Biorxiv, 2024
6ZDG
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BU of 6zdg by Molmil
Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ...
著者Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I.
登録日2020-06-14
公開日2020-07-29
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
6ZER
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BU of 6zer by Molmil
Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with EY6A Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ...
著者Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I.
登録日2020-06-16
公開日2020-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
7S8H
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BU of 7s8h by Molmil
Structure of Lassa virus glycoprotein bound to Fab 18.5C and Fab 36.1F
分子名称: 18.5C Fab Heavy Chain, 18.5C Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hastie, K.M, Enriquez, A.S.
登録日2021-09-17
公開日2022-06-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies.
Cell Rep, 39, 2022
7S8G
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BU of 7s8g by Molmil
Structure of anti-LASV Fab 25.10C with FNQI mutation
分子名称: 25.10C-FNQI Fab Heavy Chain, 25.10C-FNQI Fab Light Chain
著者Hastie, K.M, Enriquez, A.S.
登録日2021-09-17
公開日2022-06-01
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies.
Cell Rep, 39, 2022
3DVG
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BU of 3dvg by Molmil
Crystal structure of K63-specific fab Apu.3A8 bound to K63-linked di-ubiquitin
分子名称: Human IgG1 fab fragment heavy chain, Human IgG1 fab fragment light chain, Ubiquitin, ...
著者Hymowitz, S.G.
登録日2008-07-18
公開日2008-09-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell(Cambridge,Mass.), 134, 2008
9G6Z
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BU of 9g6z by Molmil
C. elegans TOFU-6 eTUDOR TOFU-1 peptide complex
分子名称: Embryonic developmental protein tofu-6, GLYCEROL, Protein tofu-1
著者Ketting, R, Falk, S.
登録日2024-07-19
公開日2024-12-04
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献piRNA processing by a trimeric Schlafen-domain nuclease.
Nature, 622, 2023

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件を2025-07-09に公開中

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