8BYA

Cryo-EM structure of SKP1-SKP2-CKS1-CDK2-CyclinA-p27KIP1 Complex

Summary for 8BYA

• Entry DOI: 10.2210/pdb8bya/pdb
• EMDB information: 16325
• Descriptor: Cyclin-dependent kinase 2, Cyclin-A2, Cyclin-dependent kinase inhibitor 1B, ... (7 entities in total)
• Functional Keywords: cell cycle, cyclin-dependent kinase, signalling, ubiquitination
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 177585.62

Authors

Rowland, R.J.,Salamina, M.,Endicott, J.A.,Noble, M.E. (deposition date: 2022-12-12, release date: 2023-06-28, Last modification date: 2023-07-19)

• Primary citation: Rowland, R.J.,Heath, R.,Maskell, D.,Thompson, R.F.,Ranson, N.A.,Blaza, J.N.,Endicott, J.A.,Noble, M.E.M.,Salamina, M.; Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.; Sci Rep, 13:10718-10718, 2023; PubMed: 37400515; DOI: 10.1038/s41598-023-37609-9

Experimental method

ELECTRON MICROSCOPY (3.38 Å)