8BZO
Cryo-EM structure of CDK2-CyclinA in complex with p27 from the SCFSKP2 E3 ligase Complex
Summary for 8BZO
Entry DOI | 10.2210/pdb8bzo/pdb |
Related | 8BYA 8BYL |
EMDB information | 16325 16327 16344 |
Descriptor | Cyclin-dependent kinase 2, Cyclin-A2, Cyclin-dependent kinase inhibitor 1B (3 entities in total) |
Functional Keywords | cell cycle, cyclin-dependent kinase, signalling, ubiquitination |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 100231.42 |
Authors | Rowland, R.J.,Salamina, M.,Endicott, J.A.,Noble, M.E. (deposition date: 2022-12-15, release date: 2023-06-28, Last modification date: 2023-07-19) |
Primary citation | Rowland, R.J.,Heath, R.,Maskell, D.,Thompson, R.F.,Ranson, N.A.,Blaza, J.N.,Endicott, J.A.,Noble, M.E.M.,Salamina, M. Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1. Sci Rep, 13:10718-10718, 2023 Cited by PubMed: 37400515DOI: 10.1038/s41598-023-37609-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
Download full validation report