8BZO
Cryo-EM structure of CDK2-CyclinA in complex with p27 from the SCFSKP2 E3 ligase Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 2 | polymer | 297 | 33943.3 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | B | Cyclin-A2 | polymer | 432 | 48609.6 | 1 | UniProt (P20248) Pfam (PF16500) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (human) | Cyclin-A,Cyclin A |
| 3 | C | Cyclin-dependent kinase inhibitor 1B | polymer | 158 | 17678.5 | 1 | UniProt (O43806) Pfam (PF02234) UniProt (by SIFTS) (P46527) In PDB | Homo sapiens (human) | Cyclin-dependent kinase inhibitor p27,p27Kip1 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 100231.4 | |
| All* | Total formula weight | 100231.4 |
