8DD4
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![BU of 8dd4 by Molmil](/molmil-images/mine/8dd4) | PI 3-kinase alpha with nanobody 3-142 | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2022-06-17 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8DD8
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![BU of 8dd8 by Molmil](/molmil-images/mine/8dd8) | PI 3-kinase alpha with nanobody 3-142, crosslinked with DSG | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2022-06-17 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8DCX
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![BU of 8dcx by Molmil](/molmil-images/mine/8dcx) | PI 3-kinase alpha with nanobody 3-159 | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2022-06-17 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8DM3
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![BU of 8dm3 by Molmil](/molmil-images/mine/8dm3) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4A8 heavy chain, ... | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM2
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![BU of 8dm2 by Molmil](/molmil-images/mine/8dm2) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein (focused refinement of NTD) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM1
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![BU of 8dm1 by Molmil](/molmil-images/mine/8dm1) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM4
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![BU of 8dm4 by Molmil](/molmil-images/mine/8dm4) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4A8 heavy chain, ... | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DMA
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![BU of 8dma by Molmil](/molmil-images/mine/8dma) | Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM6
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![BU of 8dm6 by Molmil](/molmil-images/mine/8dm6) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM7
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![BU of 8dm7 by Molmil](/molmil-images/mine/8dm7) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with mouse ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM8
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![BU of 8dm8 by Molmil](/molmil-images/mine/8dm8) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with mouse ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM9
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![BU of 8dm9 by Molmil](/molmil-images/mine/8dm9) | Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM5
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![BU of 8dm5 by Molmil](/molmil-images/mine/8dm5) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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7USE
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![BU of 7use by Molmil](/molmil-images/mine/7use) | Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site | 分子名称: | Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Ding, B, Yang, S, Chen, B, Chowdhury, S. | 登録日 | 2022-04-25 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase. Nat Commun, 13, 2022
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7USC
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![BU of 7usc by Molmil](/molmil-images/mine/7usc) | Cryo-EM structure of WAVE Regulatory Complex | 分子名称: | Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, ... | 著者 | Ding, B, Yang, S, Chen, B, Chowdhury, S. | 登録日 | 2022-04-25 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase. Nat Commun, 13, 2022
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7USD
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![BU of 7usd by Molmil](/molmil-images/mine/7usd) | Cryo-EM structure of D-site Rac1-bound WAVE Regulatory Complex | 分子名称: | Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Ding, B, Yang, S, Chen, B, Chowdhury, S. | 登録日 | 2022-04-25 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase. Nat Commun, 13, 2022
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4KY2
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![BU of 4ky2 by Molmil](/molmil-images/mine/4ky2) | Transthyretin in complex with the fluorescent folding sensor (E)-7-hydroxy-3-(4-hydroxy-3,5-dimethylstyryl)-4-methyl-2H-chromen-2-one | 分子名称: | 7-hydroxy-3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]-4-methyl-2H-chromen-2-one, Transthyretin | 著者 | Connelly, S, Wilson, I.A, Choi, S. | 登録日 | 2013-05-28 | 公開日 | 2013-08-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors. Chem.Commun.(Camb.), 49, 2013
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1WQK
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![BU of 1wqk by Molmil](/molmil-images/mine/1wqk) | Solution structure of APETx1, a specific peptide inhibitor of human Ether-a-go-go-related gene potassium channels from the venom of the sea anemone Anthopleura elegantissima: a new fold for an HERG toxin | 分子名称: | Toxin APETx1 | 著者 | Chagot, B, Diochot, S, Pimentel, C, Lazdunski, M, Darbon, H. | 登録日 | 2004-09-30 | 公開日 | 2005-03-08 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin Proteins, 59, 2005
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1WXN
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![BU of 1wxn by Molmil](/molmil-images/mine/1wxn) | Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels | 分子名称: | Toxin APETx2 | 著者 | Chagot, B, Escoubas, P, Diochot, S, Bernard, C, Lazdunski, M, Darbon, H. | 登録日 | 2005-01-27 | 公開日 | 2005-08-16 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels Protein Sci., 14, 2005
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1XDT
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![BU of 1xdt by Molmil](/molmil-images/mine/1xdt) | COMPLEX OF DIPHTHERIA TOXIN AND HEPARIN-BINDING EPIDERMAL GROWTH FACTOR | 分子名称: | DIPHTHERIA TOXIN, HEPARIN-BINDING EPIDERMAL GROWTH FACTOR | 著者 | Louie, G.V, Yang, W, Bowman, M.E, Choe, S. | 登録日 | 1997-11-18 | 公開日 | 1998-02-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor. Mol.Cell, 1, 1997
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7BDV
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![BU of 7bdv by Molmil](/molmil-images/mine/7bdv) | Structure of Can2 from Sulfobacillus thermosulfidooxidans in complex with cyclic tetra-adenylate (cA4) | 分子名称: | Can2, Cyclic tetraadenosine monophosphate (cA4) | 著者 | McQuarrie, S, McMahon, S.A, Gloster, T.M, White, M.F, Graham, S, Zhu, W, Gruschow, S. | 登録日 | 2020-12-22 | 公開日 | 2021-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence. Nucleic Acids Res., 49, 2021
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4ZIX
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![BU of 4zix by Molmil](/molmil-images/mine/4zix) | Structure of HEWL using Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Fromme, R, Ishchenko, A, Metz, M, Roy-Chowdhury, S, Basu, S, Boutet, S, Fromme, P, White, T.A, Barty, A, Spence, J.C.H, Weierstall, U, Liu, W, Cherezov, V. | 登録日 | 2015-04-28 | 公開日 | 2015-08-12 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase IUCrJ, 2, 2015
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4ZWJ
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![BU of 4zwj by Molmil](/molmil-images/mine/4zwj) | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser | 分子名称: | Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin | 著者 | Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR) | 登録日 | 2015-05-19 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.302 Å) | 主引用文献 | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature, 523, 2015
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6W17
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![BU of 6w17 by Molmil](/molmil-images/mine/6w17) | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Shaaban, M, Nolen, B.J, Chowdhury, S. | 登録日 | 2020-03-03 | 公開日 | 2020-08-12 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state. Nat.Struct.Mol.Biol., 27, 2020
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4PBU
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![BU of 4pbu by Molmil](/molmil-images/mine/4pbu) | Serial Time-resolved crystallography of Photosystem II using a femtosecond X-ray laser The S1 state | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ... | 著者 | Kupitz, C, Basu, S, Grotjohann, I, Fromme, R, Zatsepin, N, Rendek, K.N, Hunter, M, Shoeman, R.L, White, T.A, Wang, D, James, D, Yang, J.H, Cobb, D.E, Reeder, B, Sierra, R.G, Liu, H, Barty, A, Aquila, A, Deponte, D, Kirian, R.A, Bari, S, Bergkamp, J.J, Beyerlein, K, Bogan, M.J, Caleman, C, Chao, T.-C, Conrad, C.E, Davis, K.M, Fleckenstein, H, Galli, L, Hau-Riege, S.P, Kassemeyer, S, Laksmono, H, Liang, M, Lomb, L, Marchesini, S, Martin, A.V, Messerschmidt, M, Milathianaki, D, Nass, K, Ros, A, Roy-Chowdhury, S, Schmidt, K, Seibert, M, Steinbrener, J, Stellato, F, Yan, L, Yoon, C, Moore, T.A, Moore, A.L, Pushkar, Y, Williams, G.J, Boutet, S, Doak, R.B, Weierstall, U, Frank, M, Chapman, H.N, Spence, J.C.H, Fromme, P. | 登録日 | 2014-04-13 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature, 513, 2014
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