8DM3
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8
Summary for 8DM3
Entry DOI | 10.2210/pdb8dm3/pdb |
EMDB information | 27525 |
Descriptor | Spike glycoprotein, Fab 4A8 heavy chain, Fab 4A8 light chain, ... (5 entities in total) |
Functional Keywords | sars-cov-2, glycoprotein, fusion protein, viral protein, viral protein-immune system complex, omicron, ba.2, 4a8, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 9 |
Total formula weight | 600037.87 |
Authors | Zhu, X.,Saville, J.W.,Mannar, D.,Berezuk, A.M.,Cholak, S.,Tuttle, K.S.,Vahdatihassani, F.,Subramaniam, S. (deposition date: 2022-07-08, release date: 2023-01-25) |
Primary citation | Saville, J.W.,Mannar, D.,Zhu, X.,Berezuk, A.M.,Cholak, S.,Tuttle, K.S.,Vahdatihassani, F.,Subramaniam, S. Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42:111964-111964, 2023 Cited by PubMed: 36640338DOI: 10.1016/j.celrep.2022.111964 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.37 Å) |
Structure validation
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