8DM4

Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8)

Summary for 8DM4

Entry DOI	10.2210/pdb8dm4/pdb
EMDB information	27526
Descriptor	Spike glycoprotein, Fab 4A8 heavy chain, Fab 4A8 light chain, ... (5 entities in total)
Functional Keywords	sars-cov-2, glycoprotein, fusion protein, viral protein, viral protein-immune system complex, omicron, ba.2, 4a8, viral protein/immune system
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	3
Total formula weight	197226.99
Authors	Zhu, X.,Saville, J.W.,Mannar, D.,Berezuk, A.M.,Cholak, S.,Tuttle, K.S.,Vahdatihassani, F.,Subramaniam, S. (deposition date: 2022-07-08, release date: 2023-01-25)
Primary citation	Saville, J.W.,Mannar, D.,Zhu, X.,Berezuk, A.M.,Cholak, S.,Tuttle, K.S.,Vahdatihassani, F.,Subramaniam, S. Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42:111964-111964, 2023 Cited by PubMed: 36640338 DOI: 10.1016/j.celrep.2022.111964 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.45 Å)

Structure validation