8HK6
 
 | | potassium channel | | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-25 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
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8HKF
 | | ion channel | | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | | 著者 | Jiang, D.H, Zhang, Z.T. | | 登録日 | 2022-11-25 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
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7AMT
 | | Structure of LuxR with DNA (activation) | | 分子名称: | DNA (5'-D(P*AP*TP*AP*AP*TP*GP*AP*CP*AP*TP*TP*AP*CP*TP*GP*TP*AP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*TP*AP*CP*AP*GP*TP*AP*AP*TP*GP*TP*CP*AP*TP*TP*AP*T)-3'), HTH-type transcriptional regulator LuxR | | 著者 | Liu, B, Reverter, D. | | 登録日 | 2020-10-09 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression.
Nucleic Acids Res., 49, 2021
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7AMN
 | | Structure of LuxR with DNA (repression) | | 分子名称: | DNA (5'-D(P*TP*AP*TP*TP*GP*AP*TP*AP*AP*AP*AP*TP*TP*AP*TP*CP*AP*AP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*TP*GP*AP*TP*AP*AP*TP*TP*TP*TP*AP*TP*CP*AP*AP*TP*A)-3'), HTH-type transcriptional regulator LuxR | | 著者 | Liu, B, Reverter, D. | | 登録日 | 2020-10-09 | | 公開日 | 2021-03-31 | | 最終更新日 | 2021-04-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression.
Nucleic Acids Res., 49, 2021
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7KGY
 | | Beta-glucuronidase from Faecalibacterium prausnitzii bound to the inhibitor UNC10201652-glucuronide | | 分子名称: | 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, Beta-glucuronidase, GLYCEROL | | 著者 | Simpson, J.B, Redinbo, M.R. | | 登録日 | 2020-10-19 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.
Nat Commun, 13, 2022
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7KGZ
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7EMY
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7EN1
 | | Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation | | 分子名称: | (4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid, 2-HYDROXYBENZOIC ACID, 4'-PHOSPHOPANTETHEINE, ... | | 著者 | Wang, J.L, Wang, Z.J. | | 登録日 | 2021-04-15 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain.
Nat Commun, 13, 2022
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7EN2
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7ES2
 | | a mutant of glycosyktransferase in complex with UDP and Reb D | | 分子名称: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, rebaudioside D | | 著者 | Zhu, X. | | 登録日 | 2021-05-08 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
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7ERX
 | | Glycosyltransferase in complex with UDP and STB | | 分子名称: | GLYCEROL, Glycosyltransferase, Steviolbioside, ... | | 著者 | Zhu, X. | | 登録日 | 2021-05-08 | | 公開日 | 2021-12-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
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7ES1
 | | glycosyltransferase in complex with UDP and ST | | 分子名称: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, steviol-19-o-glucoside | | 著者 | Zhu, X. | | 登録日 | 2021-05-08 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
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7ERY
 | | apo form of the glycosyltransferase | | 分子名称: | Glycosyltransferase | | 著者 | Zhu, X. | | 登録日 | 2021-05-08 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
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7ES0
 | | a rice glycosyltransferase in complex with UDP and REX | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, ... | | 著者 | Zhu, X. | | 登録日 | 2021-05-08 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.395 Å) | | 主引用文献 | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
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5YVE
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5YDG
 | | Crystal structure of the Arabidopsis thaliana chloroplast RNA editing factors 2(MORF2) | | 分子名称: | Multiple organellar RNA editing factor 2, chloroplastic | | 著者 | Wang, X, Yang, J.Y, Wang, Y.L, Gao, Y.S. | | 登録日 | 2017-09-13 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | | 主引用文献 | Crystal structure of the chloroplast RNA editing factor MORF2
Biochem. Biophys. Res. Commun., 495, 2018
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6LYW
 | | Structural insight into the biological functions of Arabidopsis thaliana ACHT1 | | 分子名称: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | | 著者 | Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M. | | 登録日 | 2020-02-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
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4USG
 | | Crystal structure of PC4 W89Y mutant complex with DNA | | 分子名称: | 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*G)-3', ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 | | 著者 | Zhao, Y, Liu, J. | | 登録日 | 2014-07-08 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.973 Å) | | 主引用文献 | Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.
Sci.Rep., 5, 2015
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6LYX
 | | Crystal structure of oxidized ACHT1 | | 分子名称: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | | 著者 | Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M. | | 登録日 | 2020-02-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
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4GIH
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4GFM
 | | JAK2 kinase (JH1 domain) with 2,6-DICHLORO-N-(2-OXO-2,5-DIHYDROPYRIDIN-4-YL)BENZAMIDE | | 分子名称: | 2,6-dichloro-N-(2-oxo-2,5-dihydropyridin-4-yl)benzamide, Tyrosine-protein kinase JAK2 | | 著者 | Eigenbrot, C, Ultsch, M. | | 登録日 | 2012-08-03 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Lead identification of novel and selective TYK2 inhibitors.
Eur.J.Med.Chem., 67, 2013
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7BFZ
 | | X-ray structure of human prostate-specific membrane antigen(PSMA) in complex with a inhibitor Glu-490 | | 分子名称: | (((S)-1-carboxy-5-((E)-2-cyano-3-(5-(1-(3-methoxy-3-oxopropyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophen-2-yl)acrylamido)pentyl)carbamoyl)-L-glutamic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Rakhimbekova, A, Motlova, L, Barinka, C. | | 登録日 | 2021-01-05 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging.
Nat Commun, 12, 2021
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4GMY
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4GFO
 | | TYK2 kinase (JH1 domain) with 2,6-DICHLORO-N-(2-OXO-2,5-DIHYDROPYRIDIN-4-YL)BENZAMIDE | | 分子名称: | 1,2-ETHANEDIOL, 2,6-dichloro-N-(2-oxo-2,5-dihydropyridin-4-yl)benzamide, GLYCEROL, ... | | 著者 | Eigenbrot, C, Ultsch, M. | | 登録日 | 2012-08-03 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Lead identification of novel and selective TYK2 inhibitors.
Eur.J.Med.Chem., 67, 2013
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6IEG
 | | Crystal structure of human MTR4 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4, MAGNESIUM ION | | 著者 | Chen, J.Y, Yun, C.H. | | 登録日 | 2018-09-14 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev., 33, 2019
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