4USG

Crystal structure of PC4 W89Y mutant complex with DNA

Summary for 4USG

• Entry DOI: 10.2210/pdb4usg/pdb
• Descriptor: ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15, 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*G)-3' (3 entities in total)
• Functional Keywords: transcription
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: P53999
• Total number of polymer chains: 3
• Total formula weight: 21585.89

Authors

Zhao, Y.,Liu, J. (deposition date: 2014-07-08, release date: 2015-03-18)

• Primary citation: Huang, J.,Zhao, Y.,Liu, H.,Huang, D.,Cheng, X.,Zhao, W.,Taylor, I.A.,Liu, J.,Peng, Y.L.; Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.; Sci.Rep., 5:8789-, 2015; PubMed: 25739870; DOI: 10.1038/SREP08789

Experimental method

X-RAY DIFFRACTION (1.973 Å)